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Case Report | 10.36959/661/308 Volume 3 Issue 1
Abstract: Oral leukoplakia (OL) is certainly the most relevant lesion
that affects the oral mucosa, since it has an intrinsic potential
for malignant transformation, specifically to squamous
cell carcinoma (OSCC); and, besides, constitutes an important
issue on clinical assessment. Thus far, no treatment (or management)
can prevent the risk of malignant transformation
of OL. It is said that surgical approach can reduce (but not
eliminate) the odds of OL to develop into OSCC
Case Report | 10.36959/661/307 Volume 3 Issue 1
Abstract: Aneurysmal dermatofibroma is a rare variant of cutaneous fibrous histiocytoma (dermatofibroma) thought to be
secondary to slow extravasation of blood into the lesion. The resulting entities have different clinical and pathological
presentations that can lead to diagnostic confusion with other types of skin lesions. We discuss the defining features
of aneurysmal dermatofibroma to outline important considerations in the differential to avoid potential misdiagnosis.
Case Report | 10.36959/661/306 Volume 3 Issue 1
Abstract: At high rates of growth, the fungus can produce mycotoxins
that become airborne and inhaled. Inhalation of significant
amounts of black mold causes pulmonary mycotoxicosis.
Patients present with flu-like symptoms that include
fever, chills, nausea, cough, dyspnea, headache and myalgia. Infections are usually self-limited, requiring only supportive
Case Report | 10.36959/661/305 Volume 3 Issue 1
Abstract: Sebaceous adenomas are rare adnexal tumors that are associated with Muir-Torre syndrome. Although sebaceous adenomas are considered benign entities, this is controversial. It has been suggested that sebaceous adenomas are actually low-grade sebaceous carcinomas. In this report, we defend the view that sebaceous adenomas are in fact low-grade sebaceous carcinomas by presenting a lesion with a clinical presentation typical for sebaceous carcinoma with histopathology characteristic of sebaceous adenoma.
Case Report | 10.36959/661/304 Volume 3 Issue 1
Abstract: Cutis verticis gyrata (CVG) is a condition of excessive skin growth on the scalp leading to deep furrows and folds that resemble the gyri of the brain. There are three main categories of CVG: primary essential, primary nonessential and secondary. Primary essential is idiopathic and presents only with cutaneous alterations.
Mini Review | 10.36959/661/303 Volume 2 Issue 1
Abstract: Topical use is the main advantage for dermatological therapy due to the outer-layer features of skin. Consequently, numerous preparations are available for the dermatosis. However, the efficacy evaluation of different preparations accurately is always very difficult. Psoriasis is a common skin condition characterized by persistent erythematous scaly plaque. It is estimated about 3% population suffered from this notorious calcitrant disease.
Case Report | 10.36959/661/302 Volume 2 Issue 1
Abstract: Granuloma Annulare (GA) is a non-life threatening, granulomatous dermatosis of uncertain pathogenesis with a preference for females and mean onset after 50 years of age. Clinically, it typically appears as non-scaly, skin-colored or erythematous papules coalescing into an annular plaque. Lesions are most commonly localized in an acral distribution but can be generalized.
Case Report | 10.36959/661/301 Volume 2 Issue 1
Abstract: The management of MF-CTCL is based on a "stage-based" approach and an evaluation by a multidisciplinary team is preferred. Initial treatment in patients with local (patch/plaque) disease includes skin-directed therapies (localized or generalized), with the addition of systemic biologic therapy for refractory, or progressive disease. In patients with unfavorable prognostic features (e.g., folliculotropic or large-cell transformed MF, or B1 involvement) systemic biologic therapies may be introduced earlier in the treatment algorithm. Patients who do not respond to biologic therapy or those with very aggressive or extracutaneous disease may be treated with chemotherapy.
CASE REPORT | 10.36959/661/300 Volume 2 Issue 1
Abstract: Cutaneous metastasis of internal malignancy is an uncommon but not rare phenomenon. Renal cell carcinoma is a visceral malignancy that rarely metastasizes to the skin and typically presents as a solitary red, purple nodule when it does. We describe a case of metastatic renal cell carcinoma to the skin presenting as a zosteriform eruption.
Short Commentary | 10.36959/661/299 Volume 2 Issue 1
Abstract: Hair loss is a psychologically devastating disorder, causing grave distress to patients of all ages, genders, and nationalities. Due to the visible nature of hair loss, individuals become increasingly self-conscious, and over time may develop anxiety or depression. Furthermore, the psychological stress related to alopecia can impair functioning in social and professional arenas, affecting relationships and creating work related problems.
Case Report | 10.36959/661/298 Volume 2 Issue 1
Abstract: Lupus erythematosus panniculitis is a rare variant of lupus erythematosus. We present the case of a young man with ulcerative colitis treated with mesalazine and a history of recurrent painful and indurated lesions on his face. A diagnosis of lupus profundus was made taking in account the clinical manifestations and the histological and immunofluorescence findings. An excellent initial response and stabilization of the dermatosis was achieved with a combined treatment with antimalarial drugs and systemic corticosteroids.
Case Report | 10.36959/661/297 Volume 1 Issue 2
Abstract: Gastrointestinal surgical procedures result in approximately 100,000 ostomies per year in the United States, with over 10,00,000 people living with intestinal stomas.
Research Article | 10.36959/661/296 Volume 1 Issue 2
Abstract: Dermatology education is faced with the challenge of developing curricula for learners who possess a wide range of learning styles, strengths, and life experiences. Utilization of the V.A.R.K (Visual, Aural, Reading/Writing, Kinesthetic) model of learning, outcome-based adult-learning theory, and inclusive participatory teaching offers a unique opportunity to teach dermatology.
Case Report | 10.36959/661/295 Volume 1 Issue 2
Abstract: Hyper IgE Syndrome (HIES) is an inherited immunodeficiency syndrome with an increased susceptibility to cutaneous fungal infections. While systemic antifungals are often the therapy of choice, many non-pharmacologic treatment options have been shown to improve clearance of these infections.
Review Article | 10.36959/661/294 Volume 1 Issue 2
Abstract: The skin harbors an immune organ, made up of keratinocytes, dendritic cells (also known as Langerhans cells), as well as immune-derived nomadic cells (e.g. lymphocytes, neutrophils and eosinophils), which can respond to a variety of insults including inflammation, wound repair and infection.
Research Article | 10.36959/661/293 Volume 1 Issue 1
Abstract: Some proteins have been used as immunohistochemical markers for tumor diagnosis. Such is the case of syndecan-1, one of the four transmembrane heparin sulfate proteoglycans which are mainly present on the cellular surface.
Case Report | 10.36959/661/292 Volume 1 Issue 1
Abstract: Multiple myeloma; that constitutes 10% of all hematologic malignancies and approximately 1% of whole cancers, is a plasma cell dyscrasia. Extramedullary involvement is often seen in the upper skeletal system, besides it can be seen on the skin and breast, rarely.
Case Report | 10.36959/661/291 Volume 1 Issue 1
Abstract: Infantile Haemangioma (IH) is the most frequent benign vascular tumor of infancy, and active treatment is indicated in special situations. Topical timolol, it has been reported to be an effective and safe treatment for superficial IH, with rare adverse effects.
Research Article | 10.36959/661/290 Volume 1 Issue 1
Abstract: Pemphigus vulgaris is an autoimmune bullous disease mediated mainly by IgG autoantibodies directed to desmosome proteins. The mental health of these patients has not been extensively described in previous studies.
CASE REPORT | 10.36959/661/289 Volume 1 Issue 1
Abstract: Rothmund Thomson Syndrome (RTS) is a rare autosomal recessive disorder. It was first described in 1868 by a German ophthalmologist named August Rothmund as a syndrome consisting of bilateral juvenile cataract sand rash.
CASE REPORT | 10.36959/661/288 Volume 1 Issue 1
Abstract: Interdigital toe web infection is most frequently a polymicrobial complex disease process being caused by fungal, yeast or bacterial etiological factors, with a wide range of clinical manifestations. Treatment can prove to be difficult if the mixed etiology is not readily identified and furthermore more than one prescription is often required for eradication.
COMMENTARY | 10.36959/661/287 Volume 1 Issue 1
Abstract: Published data on cardiac indexes and superficial nutritive capillary densities from photo-protected and photo-exposed areas as well as collagen contents of skin of forearms from a large number of normal subjects over several decades of lifespan were reanalyzed using a first-order kinetic model. Excellent logarithmic linear fittings were all obtained. Slopes from the photo-protected and photo-exposed studies were virtually parallel.
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