Insights of Biomedical Research

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Review Article   |   10.36959/584/460 Volume 5 Issue 1

Chemical and Physiological Change from Calcium Carbonate to Calcium Phosphate in Skeletal Structures

Authors: Dee H. Wu, PhD, Caroline Preskitt, BS and Carolyn Gresham-Fiegel, MPH, MS
The substrates that comprise skeletal structures have evolved over more than 480 million years. We review chemical and physiological factors that may have driven the evolutionary process from an origi... Read more

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Research Article   |   10.36959/584/459 Volume 4 Issue 1

An Approximate Overview of COVID-19 Treatment Approaches by Registered Physicians of Bangladesh

Authors: Farzana Rashid, Md. Ashrafuzzaman, SK Laila Ayesha, Sadia Tanzim Islam, Niaz Mahmud and Md. Asadur Rahman
With the other countries around the world, Bangladesh is also fighting against the COVID-19 pandemic about which the current treatment and the medication procedure are not revealed worldwide. The aim ... Read more

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Review Article   |   10.36959/584/458 Volume 4 Issue 1

Balovaptan and Autism Spectrum Disorder

Authors: Diego Lopez da Silva, Lara Lídia Ventura Damasceno, Ernandes Félix Sales, Laís Kelly Maciel Rabelo, Maria Beatriz Nunes de Carvalho, Talita Maria de Oliveira Rabelo, Mayra Larisse Teixeira Alexandre, Jose Nilo Rodrigues da Silva and Gislei Frota Aragão
Balovaptan, an antagonist of the vasopressin system, has been shown to be a drug with potential to treat the main symptoms of Autism Spectrum Disorder (ASD). The objective of this work was to gather a... Read more

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Research Article   |   10.36959/584/457 Volume 4 Issue 1

TRANSCUP: A Scalable Workflow for Predicting Cancer of Unknown Primary Based on Next-Generation Transcriptome Profiling

Authors: Peng Li
Cancer of unknown primary site (CUP) accounts for 5% of all cancer diagnoses. These patients may benefit from more precise treatment when primary cancer site was identified. Advances in high-throughpu... Read more

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Research Article   |   10.36959/584/456 Volume 4 Issue 1

Prediction of Childhood Diarrhea in Bangladesh using Machine Learning Approach

Authors: Md. Maniruzzaman, Md. Shaykhul Islam, Md. Menhazul Abedin, Md Amanullah and Sadiq Hussain
Diarrhea has remained a major health problem among under-five (U5) children that leads high level of morbidity and mortality. This study is to determine the socio-demographic risk factors of diarrhea ... Read more

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Review Article   |   10.36959/584/455 Volume 4 Issue 1

Classification of Anxiety Disorders using Machine Learning Methods: A Literature Review

Authors: Muhammad Arif, Ashjan Basri, Ghufran Melibari, Taghreed Sindi, Nada Alghamdi, Nada Altalhi and Maryam Arif
This paper focuses on providing a comprehensive literature review on the application of machine learning algorithms in the diagnosis of anxiety disorder, treatment response, and prediction of onset of... Read more

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Research Article   |   10.36959/584/454 Volume 4 Issue 1

Effects of Co-occurring Genomic Alterations on Survival in Patients with KRAS-Mutant Pancreatic Cancer

Authors: Kangeun Moon, Kim Min Jae, Hyeonmin Chang and Oh Dongmyung
Pancreatic Cancer is one of the most malignant cancers with a high mortality rate. Although the effects of mutant-KRAS gene have been highly studied in the past, the effects of genes co-mutated with m... Read more

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Case Report   |   10.36959/584/453 Volume 3 Issue 1

Reversible Cardiotoxicity in a Young Patient Treated with Trastuzumab for Breast Cancer: A Case Report

Authors: Ould Amar N, Ben Bachir H, Senhadji I, Bessaih N and Toumi H
We report the case of a young patient with left breast cancer with stage IIB (T2N1M0), negative hormone receptors, HER2-positive and no particular medical history. The patient was particularly sensiti... Read more

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Research Article   |   10.36959/584/452 Volume 3 Issue 1

Effect of Vitamin D Supplementation on Clinical and Radiographic Evaluation of Oral Rehabilitation with Osseointegrated Implants

Authors: Adriano Piccolotto, Gisele Toyama, Mauro Busato and Adriane Yaeko Togashi
Vitamin D (VD) is important for the development and maintenance of bone tissue. This study used clinical and radiographic evaluations to analyze whether insufficient VD levels affect the peri-implant ... Read more

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Review Article   |   10.36959/584/451 Volume 3 Issue 1

An Overview of Sixteen Years Control Program against Rift Valley Fever in Saudi Arabia: A Review Study

Authors: Mutaz S Alhaj
Rift Valley Fever (RVF) is a serious life-threatening disease with severe clinical manifestations and health consequences for humans and a wide range of domestic animals. In September 2000, a RVF outb... Read more

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Case Study   |   10.36959/584/450 Volume 3 Issue 1

Adrenal Lesion Core Biopsy: A New Approach and an Incidental Benefit

Authors: Kim Smith
A 79-year-old male with a history of renal cell carcinoma was referred for CT guided core biopsy of a right sided 3 cm adrenal lesion. A number of vulnerable anatomical structures were adjacent to the... Read more

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Research Article   |   10.36959/584/449 Volume 3 Issue 1

Iatrogenic Bile Duct Injury and Its Management with Intensive Care Unit Process: A Single-Center Experience

Authors: Ibrahim Mungan, Sema Turan, Busra Tezcan, Bahar Aydinli, Erdal Birol Bostanci and Bulent Odemis
The delayed recognition of bile duct injury (BDI) and the challenges in its diagnosis lead to clinical variability. The management of BDI is complicated and ranges from ERCP to liver transplantation. ... Read more

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Research Article   |   10.36959/584/448 Volume 3 Issue 1

Functions of Conserved Domains of Human Polynucleotide Phosphorylase on RNA Oxidation

Authors: Sulochan Malla and Zhongwei Li
Human polynucleotide phosphorylase (hPNPase), an exoribonuclease that is primarily localized in mitochondria, plays an important role in reducing oxidized RNA and protecting cells under oxidative str... Read more

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Research Article   |   10.36959/584/446 Volume 3 Issue 1

Comparison of the Hyponatremic Effects of Erythropoietin and U-74389G

Authors: Constantinos Tsompos, Constantinos Panoulis, Konstantinos Toutouzas, Aggeliki Triantafyllou, George C Zografos, Kalliopi Tsarea, Maria Karamperi and Apostolos Papalois
This study calculated the effects on serum sodium (Na) levels, after treatment with either of 2 drugs: The erythropoietin (Epo) and the antioxidant lazaroid (L) drug U-74389G. The calculation was bas... Read more

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Review Article   |   10.36959/584/447 Volume 3 Issue 1

A New Biophysical Analysis of the Twin Paradox: The Interaction between Velocity and the Variable Biological Clock

Authors: Fred H Thaheld
Initial analysis of the twin paradox from a biophysical standpoint appears to reveal a new additional consideration that has been overlooked for over a century. That the traveling twin may come back ... Read more

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Commentary Article   |   10.36959/584/445 Volume 3 Issue 1

Management of Elderly Patients with Diabetes Mellitus from Patient-Centered Medicine

Authors: Hiroshi Bando, MD, PhD
Diabetes mellitus has become more important health problem across the world. Among them, it is not simply a medical problem with excess calories and obesity, but various differences and issues are ... Read more

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Research Article   |   10.36959/584/444 Volume 3 Issue 1

In vitro Technical Aspects of Anti-Gene IGF-I Vaccines against Glioma

Authors: Jerzy Trojan, Tatiana Castillo, Gabriela Quintero, Adama Ly, Pedro Penagos, Alexander Shevelev, You-Chun Lone, Edwin Paez, Oscar Gutierrez, Ignacio Briceno, Maciej Bierwagen, Carlos Rojas, Jaime Arias, Heliodor Kasprzak, Adis Ayala, Yuexin X Pan and Annabelle Trojan
Research on glioblastoma has demonstrated a significant increase in IGF-I gene expression in this brain tumor. After suppression of IGF-I expression using anti-gene IGF-I technologies, glioma cells be... Read more

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Opinion   |   10.36959/584/443 Volume 2 Issue 1

Need for Physician Empowerment in front of Artificial Intelligence Overruling

Authors: Francis Roger France
Artificial Intelligence (AI) has become an essential part of the computer technology industry. Machine learning, knowledge engineering, patterns identification, problem solving and robots are making i... Read more

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Research Article   |   10.36959/584/442 Volume 2 Issue 1

Influence of Confounding Evidence Based Risk Factors Triggering the Incidence of HIV Antibodies among Screened Population of Niger Delta Extraction

Authors: Azuonwu Obioma and Azuonwu Testimonies Chikanka
The Human Immunodeficiency Virus (HIV) is transmittable through body fluids such as blood, breast milk and semen. Determination of its prevalence and associated risk factors are important especially i... Read more

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Research Article   |   10.36959/584/441 Volume 2 Issue 1

Utility of Exome Sequencing Databases in Validating Genetic Variants Associated with Multiple Endocrine Neoplasia

Authors: Tyler J Mouw, Alexander Balmaceda, Tejal Brahmbhatt and Peter J DiPasco
Multiple Endocrine Neoplasia (MEN) syndromes and Familial Medullary Thyroid Cancer have a well-documented genetic origin; However, it is not always clear whether genetic variation represents a patholo... Read more

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Letter To Editor   |   10.36959/584/440 Volume 2 Issue 1

Fluoroquinolones Awareness Cipro/ciprofloxacin, Levaquin/levofloxacin, Avelox/moxifloxacin

Authors: Charles C Maack
Please recognize that I am not a Medical Doctor. Rather, I do consider myself a medical detective. I have been an avid student researching and studying prostate cancer as a survivor and continuing pat... Read more

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Research Article   |   10.36959/584/439 Volume 1 Issue 1

A Study of Nuclear Medicine Contrast Retention in Vascular Access Ports

Authors: Michael S Gossman, Huaiyu Zheng, Junling Li and Chin K Ng
Vascular access ports were investigated to determine the retention rate of injected radiotracers during PET scan acquisition. A total of 30 ports were tested, including 3 different port models from a ... Read more

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Research Article   |   10.36959/584/438 Volume 1 Issue 1

Investigation of MRI Contrast Release from Vascular Access Ports after Priming

Authors: Michael S Gossman, Zhu Mingming, Huaiyu Zheng and Chin K Ng
Vascular ports designed for venous access were injected with gadolinium contrast and imaged using MRI. Incrementally, the ports were flushed with saline and scanned to determine the amount of flush vo... Read more

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Research Article   |   10.36959/584/437 Volume 1 Issue 1

Dimensional Analysis and Constitutive Equations of Quantitative Microdialysis

Authors: CF Chen
As a membrane-based sampling technique microdialysis can be quantified by the relative recovery and the time-to-reach-the-steady-state in sampling. In this paper dimensional analysis is applied to sho... Read more

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Research Article   |   10.36959/584/436 Volume 1 Issue 1

Vitamin D Levels in Women with Intrahepatic Cholestasis of Pregnancy

Authors: Emre Canverenler, Baris Buke, Hatice Akkaya, Mustafa Bertan Demir, Cagri Guven and Gursen Gundem
To evaluate the relationship between plasma 25-hydroxyvitamin D (25(OH)D) levels in Intrahepatic Cholestasis of Pregnancy (ICP) patients.... Read more

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