Journal of Brain Disorders

 ISSN: 2578-6571

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Case Presentation   |   10.36959/524/330 Volume 2 Issue 1

Do Not Overlook Zona Herpes Ophthalmicus in a Patient Presenting with Pupil-Sparing Oculomotor Nerve Palsy

Authors: Mehtap Kocaturk, Mustafa Aksoy and Ozcan Kocaturk
Herpes Zoster (HZ), relatively common syndrome, is the result of reactivation of Varicella-Zoster Virus (VZV) that lying in the ganglion after a prior bout of varicella. Reactivation is usually caused... Read more

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RESEARCH ARTICLE   |   10.36959/524/329 Volume 1 Issue 1

Evaluation of Sequential Organ Failure Assessment (SOFA) Performance in Neurocritical Care Patients Overtime: A Retrospective Cohort Study

Authors: Mariana Rabelo de Brito, Alexandre Guimarães de Almeida Barros, Lenise Valler, Fabricio Buchdid Cardoso, Ana Paula Devite Cardoso Gasparotto, Luciana Tiziani Silva, Cristina Bueno Terzi Coelho, Desanka Dragosavac and Antônio Eiras Falcão
Prediction models are widespread used as surrogate markers of disease severity, benchmarking and resource allocation in critical care. After derivation, they should pass through validation in differen... Read more

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SHORT COMMUNICATION   |   10.36959/524/328 Volume 1 Issue 1

The History of Cerebrospinal Fluid Analysis in Multiple Sclerosis: A Great Development over the Last Centuries

Authors: Vecchio Domizia
Cerebrospinal Fluid (CSF) analysis acquired a great role in the 1990's when applied to Multiple Sclerosis (MS) diagnostic work-up. The "watery fluid" by Andreas Vesalius remained unstudied till the in... Read more

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Research Article   |   10.36959/524/327 Volume 1 Issue 1

Effect of Chinese Herbal Medicine Xixin Decoction on Aβ42 and its Regulatory Enzymes in APP/PS1 Double Transgenic Murine Brain

Authors: Diwu Yong-chang, Gu Zan, Cui Na, Yang Ke, Gu Jie, Zeng Jian, Li Xiang, Gao Yan-bin, Tang Xue-cheng and Zhai Jia-ming
To observe the effect of a Xixin decoction on learning and memory in APP/PS1 transgenic mice in addition to hippocampal ultrastructure and hippocampal Aβ42 related regulatory enzymes.... Read more

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Review Article   |   10.36959/524/326 Volume 1 Issue 1

Advances for the Pharmacotherapy of Parkinson's Disease: Pharmacological Handling of the Ca2+/cAMP Signalling Interaction

Authors: Leandro Bueno Bergantin and Afonso Caricati-Neto
Reduction of dopamine release from striatal dopaminergic neurons due to neuronal death is the main accepted concept of Parkinson's disease. Parkinson's disease begins years before a clinical diagnosis... Read more

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Review Article   |   10.36959/524/325 Volume 1 Issue 1

Statins as an Adjuvant Therapy for Psychotic Disorders: Current Evidence with a Systematic Overview of Double-Blind Placebo-Controlled Trials

Authors: Tjardo S Postma, Lyliana G Nasib, Maya J L Schutte, Marc M Bohlken, Peter Martens, Erna van't Hag, Selene R T Veerman, Marieke J H Begemann and Iris E C Sommer
Evidence is accumulating that inflammatory processes play a role in the pathophysiology of schizophrenia. This suggests that anti-inflammatory drugs might have beneficial effects in the treatment of s... Read more

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Research Article   |   10.36959/524/324 Volume 1 Issue 1

Perinatal Administration of Caffeine in Mice Affects the Spatial Memory and Motor Coordination Later in Adult Life

Authors: Alsayed A, Jamal M, Al Hoty N, Eqab S, Ahmadi N, Sameer M, Alathem A, Al Saqer M, Alsulami B and Kamal A
Data emerging that maternal consumption of moderate amount of caffeine will affect the development of the fetus and later the cognitive function of the brain. The aim of this study was to determine th... Read more

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Review Article   |   10.36959/524/323 Volume 1 Issue 1

The Discovery of the "Calcium Paradox" Due to Ca2+/Camp Interaction: Novel Adventures for the Pharmacotherapy of Neurological/Psychiatric Disorders

Authors: Leandro Bueno Bergantin and Afonso Caricati-Neto
Our discovery of the involvement of the interaction between intracellular signalling pathways mediated by Ca2+ and cAMP (Ca2+/cAMP interaction) in the neurotransmission and neuro... Read more

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