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Research Article | 10.36959/825/572 Volume 3 Issue 1
Abstract: Determination of intrafraction motion in stereotactic body radiation therapy (SBRT) of non-small-cell lung cancer (NSCLC)
usually involves generating an internal target volume (ITV) based on target segmentation in every one of the 10 phases
of a 4-dimensional computed tomography (4DCT) dataset which increases dosimetry work load substantially. This study
explores the feasibility of using a smaller number of phases to compile an ITV to get equivalent results.
Research Article | 10.36959/825/581 Volume 3 Issue 1
Abstract: Endobronchial ultrasound (EBUS) is commonly employed in the diagnostic evaluation of pulmonary nodules and for mediastinal staging of lung cancer. We hypothesized that the establishment of an onsite EBUS program would decrease the time to the diagnosis and treatment of detected malignancy in veterans seen in a dedicated pulmonary nodule clinic.
Editorial | 10.36959/825/580 Volume 3 Issue 1
Abstract: All participants understand that the information will be published anonymously, but that full anonymity cannot be guaranteed. We understand that the text and any pictures or videos published in the article will be freely available on the internet and may be seen by the general public. Pictures, videos, and text may also appear on other websites or in print, may be translated into other languages or used for commercial purposes.
Original Research | 10.36959/825/579 Volume 3 Issue 1
Abstract: The EL and EP groups did not differ substantial in objective response rate, hospital stay, or rate of leukocyte and platelet decrease. In the two groups, NSE (neuron-specific enolization enzyme) was reduced significantly after chemotherapy, but CEA (carcinoembryonic antigen) and CYFRA21 (cytokeratin 19 fragment) were not different between the two groups. In the EL group, the incidence of gastrointestinal reaction was reduced significantly and hospitalization cost was significantly increased.
Original Research Article | 10.36959/825/578 Volume 3 Issue 1
Abstract: Longitudinal inception cohort study (1974-2004) on miners who started working underground at two coal mines in Germany between 1974 and 1979. From the continuous exposure monitoring, the numbers of the shifts exposed and the shift-average concentration are available, so that long-term average and cumulative concentration of respirable coal dust and quartz component can be derived. The effects of exposure on lung function parameters (FVC, FEV1, FEV1/FVC) were estimated with generalized estimation equation (GEE) models, after adjusting for anthropometric factors, smoking behaviour, and lung function measuring devices.
Original Article | 10.36959/825/577 Volume 2 Issue 1
Abstract: Comprehensive dust control and health protection measures have been implemented to prevent coal workers' pneumoconiosis (CWP) in German collieries since several decades. The present study evaluates the risk of developing CWP related to exposure to respirable coal mine dust containing quartz.
Research Article | 10.36959/825/576 Volume 1 Issue 1
Abstract: Nivolumab (Nivo) is a programmed death receptor-1 immune check point antibody widely used in cancer.
Research Article | 10.36959/825/575 Volume 1 Issue 1
Abstract: The efficacy and safety of the Immune Check Point Inhibitors (ICPI) have been well documented. Their costs and values have received lesser attention.
Case Study | 10.36959/825/574 Volume 1 Issue 1
Abstract: Pseudoprogression is a challenging obstacle in the interpretation of therapeutic response to radiation and chemotherapies for metastatic brain lesions. Combination of stereotactic radio surgery post-treatment effects and anti-PD-1 antibody therapy may cause benign edematous enhancements in treated brain metastases which mimic tumor progression.
REVIEW ARTICLE | 10.36959/825/573 Volume 1 Issue 1
Abstract: Small Cell Lung Cancer (SCLC) represents between 13-15% of all lung cancers; however is the fifth leading cause of cancer death worldwide. SCLC prognosis remains poor despite improvements in diagnosis and treatment over the last 30 years.
Research Article | 10.36959/825/572 Volume 1 Issue 1
Abstract: To evaluate a possible influence of confounding in risk estimation for lung cancer in relation to silica dust exposure, we re-analyze a recently published exposure-response relationship using a sub-cohort of Chinese tungsten miners which has no relevant occupational confounders.
Research Article | 10.36959/825/571 Volume 1 Issue 1
Abstract: Stereotactic Body Radiation Therapy (SBRT) has rapidly emerged as a curative procedure for early stage non-small cell lung cancer (NSCLC). The ablative hypo-fractionated radiation doses used with SBRT requires very small tumor margins, making tumor motion management very important to reduce the risk of long term morbidity.
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