Annals of Lung Cancer

 ISSN: 2643-5713

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Research Article   |   10.36959/825/585 Volume 4 Issue 1

Pembrolizumab in Non-Small Cell Lung Cancer: The Role of Restricted Mean Survival Time in Estimating The Long-Term Survival Benefit

Authors: Andrea Messori PharmD, Marco Chiumente PharmD and Daniele Mengato PharmD
In comparison with the median, the restricted mean survival time (RMST) has a specific advantage because it examines the whole survival curve (like the hazard ratio) and expresses the survival outcome... Read more

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Case Report   |   10.36959/825/584 Volume 3 Issue 1

Endobronchial Sarcoma: A Case Report and Review of Literature

Authors: Anu Menon, MD, Varun Shah, MD, Adnan Hasanovic, MD, Viera Lakticova, MD
Pulmonary sarcomatoid carcinomas (PSCs) are poorly differentiated non-small cell lung carcinomas (NSCLCs) that, loosely, consist of a sarcoma-like element and/or a sarcomatous component - they represe... Read more

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Review Article   |   10.36959/825/583 Volume 3 Issue 1

Prognostic Impact of Ablative Therapy in Oligometastatic Non- Small-Cell Lung Cancer (NSCLC) with Unresectable Primary Tumor

Authors: Javier Garde-Noguera, Sara Marin-Liebana, Carmen Salvador-Coloma, José Garcia-Sánchez, Beatriz Honrubia-Peris, Corina Escoin, Nuria Piera, Oscar Juan-Vidal
Patients with Oligometastatic (OM) non-small-cell lung cancer (NSCLC) (≤ 3 metastases) might benefit from radical ablative treatment of both primary tumor and metastases. However, the role of ablati... Read more

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Research Article   |   10.36959/825/572 Volume 3 Issue 1

Dosimetric Implications of Number of Breathing Phases Used in the Definition of Internal Target Volume [ITV] in the Treatment of Non-Small Cell Lung Cancers Using Stereotactic Body Radiation Therapy (SBRT)

Authors: Von Darius Heard, Eftekhar Rajab Bolookat, Kate Martin, Jorge Gomez, Anurag K Singh and Harish Malhotra
Determination of intrafraction motion in stereotactic body radiation therapy (SBRT) of non-small-cell lung cancer (NSCLC) usually involves generating an internal target volume (ITV) based on target s... Read more

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Research Article   |   10.36959/825/581 Volume 3 Issue 1

Impact of an Onsite Endobronchial Ultrasound Program on the Time to Treatment of Cancer in Veterans

Authors: Van K Holden, MD, Stephanie Wappel, MD, Avelino C Verceles, MD, MS and Janaki Deepak MBBS
Endobronchial ultrasound (EBUS) is commonly employed in the diagnostic evaluation of pulmonary nodules and for mediastinal staging of lung cancer. We hypothesized that the establishment of an onsite E... Read more

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Editorial   |   10.36959/825/580 Volume 3 Issue 1

Nucleobindin-2 mRNA level is down regulated in KRAS-mutation lung cancer cell lines compared with EGFR/BRAF/KRAS wild-type lung cancer cell lines

Authors: Noriaki Sunaga, Hisao Imai, Junichi Okada, Eijiro Yamada, Shuichi Okada and Masanobu Yamada
All participants understand that the information will be published anonymously, but that full anonymity cannot be guaranteed. We understand that the text and any pictures or videos published in the ar... Read more

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Original Research   |   10.36959/825/579 Volume 3 Issue 1

Lobaplatin or Cisplatin Plus Etoposide for Treating Extensive Stage Small Cell Lung Cancer

Authors: Xin Zhou, Hongge Zhu, Yiyi Zhan and Chunling Liu
The EL and EP groups did not differ substantial in objective response rate, hospital stay, or rate of leukocyte and platelet decrease. In the two groups, NSE (neuron-specific enolization enzyme) was r... Read more

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Original Research Article   |   10.36959/825/578 Volume 3 Issue 1

Effect of Respirable Coal Mine Dust and Quartz on Lung Function Parameters of German Coalminers: A Longitudinal Study 1974-2004

Authors: Mei Yong, Laura Anderle, Hellmut Lenaerts, Rudolf Derwall and Peter Morfeld
Longitudinal inception cohort study (1974-2004) on miners who started working underground at two coal mines in Germany between 1974 and 1979. From the continuous exposure monitoring, the numbers of th... Read more

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Original Article   |   10.36959/825/577 Volume 2 Issue 1

The Risk of Developing Coal Workers' Pneumoconiosis in a German Inception Cohort of Coal Miners of Ruhr Area - Results after 30 Years of Follow-up

Authors: M Yong, L Anderle, H Lenaerts, R Derwall, D Brand and P Morfeld
Comprehensive dust control and health protection measures have been implemented to prevent coal workers' pneumoconiosis (CWP) in German collieries since several decades. The present study evaluates th... Read more

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Research Article   |   10.36959/825/576 Volume 1 Issue 1

Survival and Grades vs. Costs and Values of Nivolumab in Cancer; the Impact of PD-L1 Positivity

Authors: Helmy M Guirgis
Nivolumab (Nivo) is a programmed death receptor-1 immune check point antibody widely used in cancer.... Read more

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Research Article   |   10.36959/825/575 Volume 1 Issue 1

Survival and Values of the Immune Check Point Inhibitors in Non- Small-Cell Lung Cancer

Authors: Helmy M Guirgis
The efficacy and safety of the Immune Check Point Inhibitors (ICPI) have been well documented. Their costs and values have received lesser attention.... Read more

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Case Study   |   10.36959/825/574 Volume 1 Issue 1

Pseudoprogression in Non-Small Cell Lung Cancer Brain Metastases Attributable to the Anti-PD-1 Antibody Nivolumab

Authors: Sooraj John, Scott J Antonia, Trevor A Rose and Ben C Creelan
Pseudoprogression is a challenging obstacle in the interpretation of therapeutic response to radiation and chemotherapies for metastatic brain lesions. Combination of stereotactic radio surgery post-t... Read more

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REVIEW ARTICLE   |   10.36959/825/573 Volume 1 Issue 1

Radiation Therapy in the Treatment of Small Cell Lung Cancer

Authors: Guler Yavas and Cagdas Yavas
Small Cell Lung Cancer (SCLC) represents between 13-15% of all lung cancers; however is the fifth leading cause of cancer death worldwide. SCLC prognosis remains poor despite improvements in diagnosis... Read more

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Research Article   |   10.36959/825/572 Volume 1 Issue 1

Is There an Increased Risk of Lung Cancer among the Chinese Silica Cohort? - The Influence of Occupational Confounders

Authors: Yi Sun and Frank Bochmann
To evaluate a possible influence of confounding in risk estimation for lung cancer in relation to silica dust exposure, we re-analyze a recently published exposure-response relationship using a sub-co... Read more

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Research Article   |   10.36959/825/571 Volume 1 Issue 1

A Quantitative Assessment of Lung Tumor Motion under Abdominal Compression using 4D-CT Imaging

Authors: Dennis Mohatt, Jorge Gomez and Harish K Malhotra
Stereotactic Body Radiation Therapy (SBRT) has rapidly emerged as a curative procedure for early stage non-small cell lung cancer (NSCLC). The ablative hypo-fractionated radiation doses used with SBRT... Read more

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