Insights of Stem Cell Research and Therapy

Prof. Esmaiel Jabbari is a Professor in the Department of Chemical and Biomedical Engineering and the Director of Biomaterials, Tissue Engineering and Drug Delivery at the University of South Carolina, USA. He earned his Ph.D. from Purdue University in Chemical Engineering in 1993. Prof. Jabbari received Berton Rahn Award from the AO Foundation in 2012 and the Stephen Milam Award from the Oral and Maxillofacial Surgery Foundation in 2008. He was elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE) in 2013. Prof. Esmaiel Jabbari's research interests focused on Engineering 3D multi-cellular co-culture systems, Effect of Spatiotemporal delivery of growth factors, Physico-mechanical factors in the Microenvironment on function, Fate of stem cells in 3D co-culture systems for applications in skeletal tissue regeneration and cancer stem cell therapy. Bioinspired materials, Skeletal tissue engineering, etc.

Prof. Bruno Botta is a Professor of Department of Chemistry and Technology of Drug at Sapienza University of Rome, Italy and he has been nominated Deputy Vice chancellor for the Internationalization in November 2014. Prof. Botta's is Head of the Department of Chemistry and Pharmaceutical Technologies at Sapienza University of Rome since 2011. Since March, 16, 2015 he is Chair of the Cost Action CM-1407 "Challenging organic syntheses inspired by nature - from natural products chemistry to drug discovery". Prof. Bruno Botta's research interest focused on the structural elucidation and synthesis of biologically active compounds derived from living plants. Since 20 years, he has been working on the field of plant tissue cultures in combination with chemistry directed toward the understanding of biosynthetic pathways of the compounds under investigation. During the last 7 years he focused his attention on the Hedgehog (Hh) signalling pathway which plays a pivotal role in the initiation, proliferation, invasion and metastasis of various cancers.

Dr. Wael M ElShamy is a Director of Molecular Cancer Therapeutics program, Cancer institute, University of Mississippi Medical Center. He is also an Associate Professor in the Department of Radiation Oncology and Pathology at University of Mississippi Medical Center, USA. Dr. ElShamy's received his Ph.D. in Medical Biochemistry and Biophysics from Royal Karolinska Institute, Stockholm, Sweden. Dr. Wael M ElShamy’ s research interest encompass basic, clinical and translational cancer research. Research programs in his laboratory and program focus on identifying and improve treatments for breast and ovarian cancers, especially metastatic diseases, development of novel drug delivery techniques and identifying diagnostic as well as prognostic molecular biomarkers for these diseases. In his laboratory, the main focus is identifying the earliest disease lesions, and the development of targeted therapies for cancer stem cells.

Dr. August Paul R is Vice President at ICAGEN and also head of the Department of Discovery Biology, Tucson Innovation Center in Tucson Arizona, USA. He received his M.S in the Department of Genetics from University of Connecticut in 1989 and Ph.D in the Department of Cell and Molecular Biology from University of Minnesota in 1995. Dr. August Paul R's research interest includes working to advance the progression of a number of pre-clinical therapeutics in a variety of indications that includes rare neuromuscular diseases. Limited therapeutic treatments exist for these diseases, especially for muscular dystrophies and the mechanisms for employing cell therapy in these diseases in not well established.

Prof. Ken H Young is a Professor at The University of Texas MD Anderson Cancer Center Houston, TX, USA. He received his MD from Zhejiang University School of Medicine, Zhejiang, China in 1984 and PhD in the Department of Pathology and Laboratory Medicine from University of Lund School of Medicine, Malmo, Sweden in 1995. Prof.Young's was awarded with Lymphoma SPORE DRP Award, The University of Texas MD Anderson Cancer Center in 2011-2013 and Myeloma SPORE 2nd DRP Award, The University of Texas MD Anderson Cancer Center in 2014-2015. Prof. Ken H Young's research interest focus on Acute myelogenous leukemia, Peripheral T-cell lymphoma, Dendritic and Histiocytic Neoplasms, Myelodysplastic Syndrome, Hodgkin lymphoma, Bone Marrow and Peripheral Blood Pathology, Lymphoid Neoplasms, etc

Prof. Sanjay Gupta is a Professor & Research Director and holds Carter Kissell Endowed Chair in Urologic Oncology in the Department of Urology at Case Western Reserve University and The Urology Institute at the University Hospitals Case Medical Center. He also holds secondary appointments in the Departments of Nutrition and Division of General Medical Sciences at Case Comprehensive Cancer Center. Dr. Gupta's has joint appointment as Research Scientist at the Louis Stokes VA Medical Center, Cleveland, Ohio. Prof. Gupta's awarded with American Urological Association Award and DPD Deficiency Foundation Award in 2016. Prof. Sanjay Gupta's research interest involves basic, translational and clinical areas of focus. In basic research his focus is to understand the risk factors and mechanisms of prostatic and bladder diseases and develop appropriate biomarkers for early detection and prognosis. Translational research focus is to identify novel targets to monitor the efficacy of various synthetic and natural agents and develop them as chemo preventatives/therapeutics. His clinical research interests are translation of bench research to its application in clinics.

Prof. Alexander Birbrair is a Professor of Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. He received his Ph.D in Neuroscience under the mentorship of Osvaldo Delbono. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques.

Prof. Ssang Goo Cho is a Professor in the Department of Stem Cell & Regenerative Biotechnology at Konkuk University, Korea and and also as a director of Incurable disease animal model and stem cell institute (IDASI). He received B.S., M.S., and Ph.D. degrees in Genetic Engineering from Korea University, Republic of Korea. Prof. Cho's was honored with postdoctoral fellowship at Ruttenberg Cancer Center, Mount Sinai School of Medicine, New York, USA. Prof. Ssang Goo Cho's research interest incudes Signaling pathways in stem, cancer, and cancer stem cells, Molecular mechanism of cellular reprogramming, Apoptosis and autophagy, Cancer stem cells, induced pluripotent stem cells, Pancreatic beta-cell differentiation, Pancreatic cancer cells.

Prof. Parsons Xuejun Huang in the Department of Regenerative Medicine, San Diego Regenerative Medicine Institute,San Diego CA, USA. She received her PhD in Biochemistry, Molecular, and Cell Biology from Cornell University in 1998, and completed her PostDoc studies as a Leukemia and Lymphoma Society Research Fellow at University of California at San Diego in 2002. Prof. Huang's was awarded a NIH mentored research scientist career development award (NIH K01AG024496, titled "Epigenetic Controls in hESC Dopaminergic Fate") in 2005 for successful transition of her career into the human stem cell field as PI. Prof. Parsons Xuejun Huang's research interest includes stem cell biology, regenerative medicine, neural regeneration, human pluripotent stem cell, human embryonic stem cells, neural stem cells, neuronal progenitor, neurological disorders, neurodegenerative disease, cardiac stem cell, heart disease, cell therapy, tissue engineering, cancer stem cell.

Dr. Oriana Trubiani is an Associate Professor of Histology Anatomy, and she is head of the laboratory for Stem Cells and Regenerative Medicine at the Department of Medical, Oral and Biotechnological Sciences of "G. d'Annunzio" University, Chieti, Italy. Dr. Oriana Trubiani's research interests focused on the understanding mechanisms that regulate and leading the stem cells activity on tissue homeostasis and repair throughout the identification of intracellular pathway that regulate the regenerative potential. She leads a multidisciplinary research group focused on both high quality fundamental science and translation for human health. Research in regenerative medicine includes of stem cells differentiation, 3D scaffold evaluation, the design of novel living constructs and new approaches towards tissue regeneration and the use of stem cells in cell therapy

Dr. Bhuvnesh K Sharma is a Senior Director in the Department of R&D Translational Oncology at ScyTeK Laboratories Inc., Logan UT. He did his Post-Doctoral Trainings in Molecular Oncology/ Immuno-Virology at St. Mary’s Hospital Medical School, London, UK and Johns Hopkins University Medical Institutions, Baltimore, MD, USA. Dr. Sharma's has previously served as Adjunct Associate Professor, Georgetown University. School of Medicine Washington DC and Senior Scientist, Weinberg Cancer Institute MedStar Health Franklin Square Medical Center, Baltimore. Dr. Bhuvnesh K Sharma's research interest focused on Preclinical Cancer Research, Cancer Stem Cell Research, Genomic Tumor Pathology, Diagnostic Immunohistochemistry, Predictive Cancer Tissue Biomarkers, Tumor Immuno-Virology, Companion Cancer Diagnostics, Exploratory Adjuvant Tumor Immunotherapy

Dr. Susan M Majka is an Associate Professor of Medicine; Allergy, Pulmonary & Critical Care Medicine; Cell & Developmental Biology; Pathology, Microbiology & Immunology; Vanderbilt Center for Stem Cell Biology and Vanderbilt Vascular Biology Center at Vanderbilt University Medical Center, Nashville, Tennessee, USA. She received her Ph.D in Cellular & Molecular Biology from University of New Mexico-Health Sciences Center in 1997. Dr. Majka honored with Mentor: Chancellors Award for Excellence in Undergraduate Research; Finalist The Cournand & Comroe Young Investigator Prize In CPCC-AHA and FASEB Abstract Selected for Consideration: The Hermann Rahn Award for Excellence in Pulmonary Research and oral presentation in 2014. Dr. Susan M Majka's research interests includes Understanding how adult tissue resident mesenchymal progenitor cells regulate microvascular tissue homeostasis as well as remodeling at the expense of repair, Vasculopathy influences the development of chronic diseases, Development and course of chronic lung diseases (including pulmonary vasculopathy, fibrosis, emphysema/COPD, systemic sclerosis and hypertension, Patient derived human lung MPC and induced pluripotent stem cell (iPS) derived mesenchymal cells.Dr. Susan M Majka is an Associate Professor of Medicine; Allergy, Pulmonary & Critical Care Medicine; Cell & Developmental Biology; Pathology, Microbiology & Immunology; Vanderbilt Center for Stem Cell Biology and Vanderbilt Vascular Biology Center at Vanderbilt University Medical Center, Nashville, Tennessee, USA. She received her Ph.D in Cellular & Molecular Biology from University of New Mexico-Health Sciences Center in 1997. Dr. Majka honored with Mentor: Chancellors Award for Excellence in Undergraduate Research; Finalist The Cournand & Comroe Young Investigator Prize In CPCC-AHA and FASEB Abstract Selected for Consideration: The Hermann Rahn Award for Excellence in Pulmonary Research and oral presentation in 2014. Dr. Susan M Majka's research interests includes Understanding how adult tissue resident mesenchymal progenitor cells regulate microvascular tissue homeostasis as well as remodeling at the expense of repair, Vasculopathy influences the development of chronic diseases, Development and course of chronic lung diseases (including pulmonary vasculopathy, fibrosis, emphysema/COPD, systemic sclerosis and hypertension, Patient derived human lung MPC and induced pluripotent stem cell (iPS) derived mesenchymal cells.

Dr. Hideyo Yasuda is a Senior Researcher in the Department of Stem Cell and Regenerating Technology at Konkuk University, South Korea. Now he retired from the professor position in MD anderson cancer center, Houston, TX. Dr. Yasuda received his Ph.D in Cell Biology and Molecular Biology from Graduate School of University of Tokyo, Japan in 1977. Dr. Yasuda honored with Award for Excellent Pharmaceutical Research, The Research Foundation for Pharmaceutical Sciences, 1990; Award for Scientific Research, The Naito Foundation, 1998; Award for Excellent Cancer Research, The SAGAWA Foundation for Promotion of Cancer Research, 2000 and Award for Life Science, The Uehara Memorial Foundation, 2003. Dr. Hideyo Yasuda's research interests focuses on the regulatory mechanism of the mammalian cell cycle, proteolysis, post- translational modification of protein, differentition, and cancer cell growth.

Dr. Ying Sun is an Associate Professor in Division of Human Genetics at Cincinnati Children's Hospital Medical Center, USA. Dr. Sun received her Ph.D. in Department of Pharmacology and Biophysics in 1993 from University of Cincinnati and B.S Degree from Beijing University in 1982. She was honored with Chinese Government National Visiting Scholar Award, Beijing, China, 1986 and University Graduate Scholarship, University of Cincinnati, 1987-1992. Dr. Ying Sun's research interest focused on understanding the pathogenesis as a foundation for development of effective therapies. Research include genomic editing and stem cell therapies, preclinical research on enzyme therapy, cell therapy and pharmacological agents, disease specific lipidomics to the relationship of Gaucher disease mutations and Parkinson's disease, and glycosphingolipids metabolism in neurodegeneration.

Dr. Oriana Trubiani is an Associate Professor of Histology Anatomy, and she is head of the laboratory for Stem Cells and Regenerative Medicine at the Department of Medical, Oral and Biotechnological Sciences of "G. d'Annunzio" University, Chieti, Italy. Dr. Oriana Trubiani's research interests focused on the understanding mechanisms that regulate and leading the stem cells activity on tissue homeostasis and repair throughout the identification of intracellular pathway that regulate the regenerative potential. She leads a multidisciplinary research group focused on both high quality fundamental science and translation for human health. Research in regenerative medicine includes of stem cells differentiation, 3D scaffold evaluation, the design of novel living constructs and new approaches towards tissue regeneration and the use of stem cells in cell therapy.