Clinical Hematology and Research Archives

Clinical Image | 10.36959/831/392 Volume 7 Issue 1

Microgranular Acute Promyelocytic Leukaemia (APML) with FLT3p.N676K

Authors: Ke Xu

A 46-year-old male presented with easy bruising, easy bleeding, haemoglobin 68 g/L, white blood cells 11.67 × 10⁹/L, platelet 17 × 10⁹/L, PT 15.1 seconds, APTT 25 secon... Read more

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Case Report | 10.36959/831/391 Volume 6 Issue 1

First Documented Case of Massive Pulmonary Embolism and Massive Ilio-Femoral Deep Venous Thrombosis Treated Simultaneously

Authors: Harinder Singh Bedi, MCh, Jiten Deep Singh, MCh, Vikram Arora, MD, Luv Luthra, MCh and Yash Vyas, BSC

Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE) cause major morbidity and mortality. A PE develops from a DVT. Surprisingly there are very few reports of a DVT and a PE being documented toget... Read more

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Case Report | 10.36959/831/390 Volume 5 Issue 1

Correlation of SLC19A1 A80G and MTHFR C677T Polymorphisms with Methotrexate-Induced Hepatotoxicity in a Paediatric Acute Lymphoblastic Leukaemia Patient: A Case Report

Authors: Karen Ilenia Álvarez Tosco, MS, María Micaela Viña Romero, MS, Héctor González Méndez, MD, Javier Merino Alonso, PhD, Gloria Julia Nazco Casariego, PhD, Ruth Ramos Díaz, PhD and Fernando Gutiérrez Nicolás, PhD

High-dose methotrexate is a crucial component of acute lymphoblastic leukaemia (ALL) treatment regimens. Adherence and tolerance to the treatment plan are critical factors to achieve the prognostic go... Read more

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Research Article | 10.36959/831/389 Volume 5 Issue 1

Significance of Some Markers of Systemic Inflammation and Platelet Activation in Patients with Type 2 Diabetes Mellitus in the Enugu State University of Science and Technology Teaching Hospital Enugu State Nigeria

Authors: Ogbuabor Alphonsus Ogbonna, Onyia Nkiruka Loius and Nwobodo Humphrey Afam

Diabetes mellitus has over the years become a public health challenge and a complex disease which is characterized by chronic hyperglycemia that results in microvascular and macro vascular complicatio... Read more

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Research Article | 10.36959/831/388 Volume 5 Issue 1

Research of Pencil Cells and Precheratocyte in Patients with Microcytic Anemia- Our Experience

Authors: Antonella Mileti, Maria Pepe, Luigia Loiodice, Domenica Leogrande, Vincenzo Brescia, Ersilia Cleopazzo, Michele Pasculli, Francesca Castellaneta, Roberto Lovero, Salvatore Scacco and Francesca Di Serio

The most frequent forms of microcytic anemia are: Iron deficiency anemia (IDA), β-thalassemia and chronic disease anemia (ACD) alongside the traditional laboratory parameters (RDW, iron, ferritin, et... Read more

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Case Report | 10.36959/831/387 Volume 5 Issue 1

The Role of Clinical Prediction Scores in Thrombotic Thrombocytopenic Purpura

Authors: Sevoyan A, Chakhoyan A, Ghazaryan P, Ter Grigoryan A, Hakobyan Y, Grigoryan H, Oseyan H and Martirosyan N

Thrombotic thrombocytopenic purpura (TTP) is a fulminant and life-threatening blood disorder characterized by a pentad of microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure, feve... Read more

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Case Report | 10.36959/831/386 Volume 5 Issue 1

Failed Reticulocyte Count in a Patient after Cardiac Surgery

Authors: Norbert Ostendorf, MD and Veronika Jennissen, MD

The evaluation of erythropoesis by reticulocyte analysis is a mainstay in the diagnosis of anaemia. The classical method comprises staining with brilliant cresyl blue and counting the number of reticu... Read more

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Original Article | 10.36959/831/385 Volume 4 Issue 1

Relationship of Transfusion Amounts to Old Age and Survival of Adult Acute Leukemia Patients Who Survived beyond 100 Days

Authors: Jeong-Shi Lin, Jia-Ching Lin, Ying-Ju Chen, Sheng-Hsuan Chien, Chun-Yu Liu and Tzeon-Jye Chiou

The ageing process puts the elderly at risk of developing anemia and thrombocytopenia with increased risk of transfusions. Patients with increased transfusion requirements may be at increased risk of ... Read more

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Research Article | 10.36959/831/384 Volume 4 Issue 1

Neutrophil to Lymphocite Ratio Predicts Overall Survival in Newly Diagnosed Hodgkin Lymphoma Patients-Single Centre Experience

Authors: Jelena Hajder, Natasa Stanisavljević, Dragomir Marisavljević, Olivera Marković, Radmila Zivković and Vladimir Jurišić

This retrospective analysis included 83 newly diagnosed patients with HL followed up from 2001-2015. ROC curve analysis was used to determine the optimal cut-off values for overall survival. Univariat... Read more

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Case Report | 10.36959/831/383 Volume 4 Issue 1

Acquired Amegakaryocytic Thrombocytopenic Purpura that Presented as Cyclic Thrombocytopenia Associated with Anti- Phospholipid Antibody Syndrome

Authors: Yoko Katsuragawa-Taminishi, Daisuke Ide, Saori Maegawa-Matsui, Shin-ichi Fuchida, Mayumi Hatsuse, Satoshi Murakami, Junya Kuroda and Chihiro Shimazaki

A 52-year-old female, who had been taking prednisolone (PSL) for anti-phospholipid antibody syndrome (APS), was admitted to our hospital because of repeated nasal bleeding, purpura and petechiae of th... Read more

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Research Article | 10.36959/831/382 Volume 3 Issue 1

Evaluation of Safety of Pancreaticoduodenectomy for Patients with Benign Conditions

Authors: Bangren Xu, Xiaowei Yuan, Tiffany Wong, TT Cheung, CM Lo, Ji Ren, Siyuan Qiu, Chunhong Liu and Hongtao Zhu

Pancreaticoduodenectomy (PD) is a complex and high-risk surgical procedure with substantial mortality and morbidity. Selected patients with benign conditions may need PD in case of ambiguous tissue di... Read more

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Case Series | 10.36959/831/381 Volume 3 Issue 1

Management of Cholecystectomy in a Patient with Severe Von Willebrand Disease

Authors: Hanaa Bencharef, Abdelaziz Fadil, Latifa Loukhmasse and Bouchra Oukkache

Von Willebrand disease is the most common hereditary bleeding disorder; its Type 3 is the most severe form with a high risk for surgical bleeding, both intraoperatively and during the postoperative pe... Read more

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Case Series | 10.36959/831/380 Volume 3 Issue 1

Myeloproliferative Neoplasms with Subsequent Development of Chronic Myelogenous Leukemia: A Case Series

Authors: Reap L, Patel S, Kim SH, Shammo JM and Terebelo H

Myeloproliferative neoplasms (MPN) are broadly divided by the presence or absence of the Philadelphia chromosome (Ph), with its presence considered a major marker of chronic myelogenous leukemia (CML)... Read more

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Research Article | 10.36959/831/379 Volume 2 Issue 1

Prognostic Significance of MIPI and MIPI-B Scoring Systems for Mantle Cell Lymphoma in the Turkish Population

Authors: Mehmet Ali Ucar, Simten Dagdas, Murat Albayrak, Osman Sahin, Funda Ceran, Mesude Falay and Gulsum Ozet

Our objective in this study is assessment of Mantle Cell Lymphoma International Prognostic Index (MIPI) and biological MIPI (MIPI-B) scores as prognostic markers based on real-life data of patients d... Read more

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Case Report | 10.36959/831/378 Volume 2 Issue 1

Factor VII Arg304Gln (FVII Padua) in North and South Americas: The Influence of Past

Authors: Antonio Girolami, Silvia Ferrari, Elisabetta Cosi and Bruno Girolami

All homozygous cases of this FVII defect reported from the Mediterranean countries and from North and South America have been evaluated. Both papers with genetically proven cases and those without mo... Read more

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CASE REPORT | 10.36959/831/377 Volume 1 Issue 1

Development of Hodgkin's Lymphoma-Like Post-Transplant Lymphoproliferative Disorder after Tandem Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma

Authors: Masaaki Tsuji, Tatsuki Uchiyama, Chisaki Mizumoto, Tomoharu Takeoka, Kenjiro Tomo and Tatsuharu Ohno

Post Transplant Lymphoproliferative Disorders (PTLDs) are serious complication after solid organ or Hematopoietic Stem Cell Transplantation (HSCT). Hodgkin's Lymphoma (HL)-like PTLD is grouped with HL... Read more

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REVIEW ARTICLE | 10.36959/831/376 Volume 1 Issue 1

Patterns of Discharge Disposition among Patients Diagnosed with Venous Thromboembolism in the Emergency Department: A Multicenter Retrospective Cohort Evaluation

Authors: Marielys Figueroa-Sierra, Joanna Young, Blake Goodbar and Stephanie Parks Taylor

Venous Thromboembolism (VTE) includes both Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE) and can range from asymptomatic to fatal. It is a common medical condition annually affecting at lea... Read more

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Case Report | 10.36959/831/375 Volume 1 Issue 1

Intravascular Hemolysis as a Presenting Feature of Acute Cytomegalovirus Infection in an Immunocompetent Patient

Authors: Juliana Perez Botero, Alexandra P Wolanskyj and Brianna E Vaa

Acute Cytomegalovirus (CMV) infection seldom presents with hemolytic anemia in an immunocompetent host. When hemolysis does occur, it is typically immune mediated and extravascular, but can be intrava... Read more

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Case Report | 10.36959/831/374 Volume 1 Issue 1

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) or Stevens - Johnson syndrome (SJS): Does the Name Matter!

Authors: Awad Magbri

The case is of 23-year-old Caucasian male who fell from 30 feet height in a suicidal attempt. He sustained multiple orthopedic fractures including hips, left lower ribs, and right radius at the elbow.... Read more

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