Clinical Diabetes and Research

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Clinical Diabetes and Research Archives

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Case Report   |   10.36959/647/497 Volume 5 Issue 1

Euglycemic Diabetic Ketoacidosis in a Diabetic Patient Treated with SGLT2 Inhibitor

Authors: Olga Lavrynenko, MD, PhD, Hector Santos, MD, Amando Garza, MD, Rayan Qazi, MD, and Leopoldo Cobos, MD
Diabetic ketoacidosis (DKA) is a life - threatening complication and must be diagnosed and treated promptly and aggressively. The classic triad of DKA is: Hyperglycemia (blood glucose (BG) > 250 mg/dl... Read more

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Short Report   |   10.36959/647/496 Volume 5 Issue 1

High Serum Insulin Level in Neonatal Hypoglycemia: A False Expectation

Authors: Shabih Manzar, MD
Hyperinsulinemia literally means high serum insulin level (Hyper: Excess, over, beyond, exaggerated). The Pediatric Endocrine Society recommends measuring serum insulin in the evaluation of persistent... Read more

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Research Article   |   10.36959/647/495 Volume 5 Issue 1

Disposition Index (DI) is not Improved with High-Intensity Intermittent Exercise in Adults with Hyperinsulinemia and Pre-Diabetes

Authors: Oana Ancu, Jane Naufahu, Richie Barclay, Peter Watt and Richard WA Mackenzie
The progression from pre-diabetes to overt type 2 diabetes is largely attributed to β-cell dysfunction and reduced insulin responsiveness. Exercise improves β-cell function in type 2 diabetics, howe... Read more

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Research Article   |   10.36959/647/494 Volume 4 Issue 1

Examining the Relationship between Stress and Insulin Resistance in Civilians and Veterans

Authors: Joshua Minks, PhD, RN
Stressful life events, particularly traumatic events, can produce a considerable if not significant stress, inducing insulin resistance and potentially type 2 diabetes mellitus (T2DM) secondary to hyp... Read more

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Research Article   |   10.36959/647/493 Volume 3 Issue 1

Suppression of Free Fatty Acids by Oral Glucose in Patients with Cystic Fibrosis

Authors: Marie-Angela Schnyder, Oliver Tschopp, Cornelia Zwimpfer, Christian Benden and Christoph Schmid
The oral glucose tolerance test (OGTT) is part of the routine management and readily detects impaired insulin secretion in the majority of adult patients with cystic fibrosis (CF). To assess an activi... Read more

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Case Report   |   10.36959/647/492 Volume 2 Issue 1

SGLT2 Inhibition May Precipitate Euglycemic DKA after Bariatric Surgery

Authors: Hassan Elasha, Ali Mekki Elsheikh, Wafic Wafa and Karim Meeran
SGLT2 inhibitors (SGLT2Is) lower blood glucose through inhibition of glucose reabsorption in the proximal renal tubules via an insulin independent mechanism. They have a low risk of hypoglycaemia with... Read more

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Review Article   |   10.36959/647/491 Volume 1 Issue 1

Ethical Issues Attendant with the Current Pandemic of Diabetes

Authors: Wayne X Shandera
The International Diabetes Foundation (IDF) estimates that 415 million of the 7 billion global inhabitants have diabetes and this number is estimated to surge to 642 million by 2040.... Read more

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Review Article   |   10.36959/647/490 Volume 1 Issue 1

Therapeutic Agents Targeting at AGE-RAGE Axis for the Treatment of Diabetes and Cardiovascular Disease: A Review of Clinical Evidence

Authors: Hong Sheng Cheng, So Ha Ton and Khalid Abdul Kadir
Advanced Glycation End Products (AGEs), together with its receptor (RAGE) are known to play a predominant role in the onset of diabetic micro- and macrovascular diseases.... Read more

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Brief Report   |   10.36959/647/489 Volume 1 Issue 1

Glargine U300 Insulin as a Better Option than Degludec U100 to Treat a Congenital Generalized Lipodystrophy Patient

Authors: Josivan G Lima, Natalia N Lima, Ricardo LM Lima, Maria FP Baracho and Lucia HC Nobrega
Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a rare autosomal recessive syndrome characterized by a generalized lack of adipose tissue, evolving with diabetes mellitus, dyslipidemia, and hepat... Read more

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Research Article   |   10.36959/647/488 Volume 1 Issue 1

Investigation of Pharmacological Responses to an Anti-Diabetic Drug Pioglitazone in Female Spontaneously Diabetic Torii (SDT) Fatty Rats, A New Obese Type 2 Diabetic Rat

Authors: Murai Y, Miyajima K, Shinohara M, Yamada T and Ohta T
Rigorous glycemic control is essential to prevent the development of diabetes and onset of diabetic complications. Peroxisome proliferator-activated receptor (PPAR) γ activator pioglitazone is an... Read more

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CASE REPORT   |   10.36959/647/487 Volume 1 Issue 1

Immune Response to Influenza Vaccination in Older Adults: Interactions with Type 2 Diabetes

Authors: Haleh Rokni, Nisha Nigil Haroon and Janet E McElhaney
Type 2 diabetes mellitus (T2DM) is one of the most common disorders among adults over age 65. Both humoral and cellular immune responses are negatively affected by diabetes. Therefore infections such ... Read more

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RESEARCH ARTICLE   |   10.36959/647/486 Volume 1 Issue 1

Fish Oil Intake during Pregnancy and Lactation in Rats Has Different Long-Term Effects on Glucose-Insulin Relationships in Male Pups Depending on Their Age

Authors: Lopez Soldado I, Ortega Senovilla H and Herrera E
During pregnancy, polyunsaturated fatty acids are essential for fetal development. The fetus is unable to synthesize them and they have to come from the mother. Fish oil supplements (rich in docosahex... Read more

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