Journal of Drug Design and Development

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Table of Content: Volume 2, Issue 1

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Research Article Pages 44-48

5,10-Dihydro-7,8-Dimethyl Alloxazine as an Anticancer Agent from Lumichrome of Riboflavin

Authors: Shafia Farhana Etu, Ali Alqahtani and Nazmul Qais

Abstract: Scientists are continuing their relentless endeavor to find a remedy for cancer or therapeutic agents which will minimize the growing burden of this seemingly incurable disease to a great extent. From literature review, we got the insight that a photoproduct of riboflavin named lumichrome has anticancer effect against lung cancer and this demands working on this compound and evaluation of anticancer activity.

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Research Article Pages 29-43

Application of Molecular Descriptor Derived from Weighted Line Graph in Narcosis-QSAR

Authors: Chandana Adhikari and BK Mishra

Abstract: Topological indices derived from line graph are in use since 1980’s and are mostly used in deriving Quantitative Structure- Property Relationships. Never before weighted line graphs were used for this purpose. A descriptor, L2, derived from weighted line graph has been used in modeling Quantitative Structure-Activity Relationship (QSAR) for the narcotic activity of 123 diverse organic compounds.

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