Clinical Diabetes and Research

Research Article Pages 43-49

Suppression of Free Fatty Acids by Oral Glucose in Patients with Cystic Fibrosis

Authors: Marie-Angela Schnyder, Oliver Tschopp, Cornelia Zwimpfer, Christian Benden and Christoph Schmid

Abstract: The oral glucose tolerance test (OGTT) is part of the routine management and readily detects impaired insulin secretion in the majority of adult patients with cystic fibrosis (CF). To assess an activity of endogeneous insulin on adipose tissue in these patients, we analyzed serum levels of insulin and free fatty acids (FFA) in response to oral glucose since glucose-induced insulin decreases FFA and thus, suppression of FFA reflects an insulin effect on adipose tissue.

| | |