ISSN: 2578-6490
Associate Professor
Departments of Psychiatry, Neuroscience & Physiology
New York University Langone Medical Center
New York,
United States of America
Stephen D. Ginsberg, Ph.D. is a Research Scientist at the Center for Dementia Research, Nathan Kline Institute (NKI) and a Tenured Associate Professor in the Departments of Psychiatry, Neuroscience & Physiology, New York University Langone Medical Center (NYULMC). Dr. Ginsberg received his Ph.D. in Neurobiology at the Mount Sinai Medical Center. He received postdoctoral training in the Division of Neuropathology, Department of Pathology, The Johns Hopkins University School of Medicine and Center for Neurodegenerative Disease Research, Department of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine. The principal focus of the Ginsberg laboratory is to delineate cellular and molecular mechanisms underlying selective vulnerability to neurodegeneration. The hippocampal formation, neocortex, and cholinergic basal forebrain, brain regions critical for attention, learning, and memory, are targeted for molecular and cellular based analyses in animal and cellular models of neurodegeneration as well as in postmortem human brains. A multidisciplinary approach of state-of-the-art functional transcriptomics and proteomics approaches combined with immunocytochemical and cell biological techniques is utilized as part of the experimental design. Particular emphasis is placed upon analyzing the fingerprint of single neuronal populations as a means of understanding the complex cascade of molecular and cellular events that occurs under pathologic conditions such as aging, Alzheimer’s disease, Down syndrome, and mild cognitive impairment.
