ISSN: 2578-6490
Professor
Department of Biomedical Sciences
University of North Dakota, School of Medicine and Health Sciences
Public university in Grand Forks, North Dakota
Tel: 701-777-2522
Othman Ghribi has completed his Ph.D in Neuropharmacology in 1994 at the University René Descartes, Paris France, and postdoctoral studies from The University of Quebec (1996-1999). Dr Ghribi then joined the Department of Pathology at the University of Virginia (1999-2004) and the Department of Basic Sciences at the University of North Dakota School of Medicine in 2004. He has published more than 70 papers in reputed journals and serving on the Editorial Board of The Journal of Alzheimer’s Disease, Current Alzheimer’s disease, and the Journal of Neurodegenerative Diseases. Dr. Ghribi’s current research is funded by the national Institute of Health and focuses on the role of environmental factors (chemical and dietary) and genetic susceptibility in the pathophysiology of Alzheimer’s and Parkinson’s diseases. His Research Interests includes For the last years, our research is focused on identifying environmental as well as genetic factors that trigger or mediate Alzheimer’s disease pathology. My laboratory has published numerous contributions showing that high cholesterol diets and cholesterol oxidized products (oxysterols) induce pathological features relevant to the sporadic forms of Alzheimer’s disease. Our current NIH-funded research is focused on the possible role diets rich in saturated free fatty acids play in the pathogenesis of Alzheimer’s disease in animal models. We specifically focus on the potential role of the endoplasmic reticulum stress and lipid dyshomeostasis in inducing neurodegeneration.
