Annals of Nephrology

 ISSN: 2642-4827

Annals of Nephrology

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Table of Content: Volume 5, Issue 1

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Research Article Pages 78-83

Evaluation of Children with Nephrotic Syndrome: A Single- Center Experience

Authors: Cem Alatas, Yilmaz Tabel, Ahmet Taner Elmas, and Senay Zirhli Selcuk

Abstract: Nephrotic syndrome (NS) is one of the most frequent occurring chronic kidney diseases in children. In this study, our aim was to assess the sociodemographic structure, determination of clinical data, diagnostic approaches, treatment methods applied and the factors effective on prognosis in patients followed with a diagnosis of nephrotic syndrome in our clinic.

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Case Report Pages 75-77

Two Successful Pregnancies in a Woman without Kidneys: A Case Report

Authors: Anna Curtis, Christian Lamb, Sarah Atallah, Saras Singh, and Amit Patel

Abstract: Bilateral nephrectomy is a rarely used approach to control refractory hypertension in patients with anuric end-stage renal disease (ESRD) who already require dialysis. This procedure results in complete dependence on hemo- or peritoneal dialysis to maintain metabolic homeostasis and has fallen out of favor given advancements in anti-hypertensive pharmacotherapy.

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Case Report Pages 71-74

A Patient of Crescentic Glomerulonephritis with Positive Anti Myeloperoxidase Antibodies and Immunoglobulin a Deposits on Immunofluorescence: The Conundrum Continues

Authors: Mayank Chawla, Tan Puay Hoon and Shashidhar Baikunje

Abstract: Immunoglobulin (Ig)A nephropathy is the commonest type of primary glomerulonephritis (GN) in the world, with an estimated incidence of 2.5/100000 adults/year. It can co-exist with systemic conditions and is a common cause of crescentic GN. Antineutrophilic cytoplasmic antibody (ANCA) associated vasculitis can present as necrotizing, crescentic GN with pauci immune features on immunofluorescence on renal biopsy.

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Retrospective Study Pages 60-70

Switching between Dialysis Modality: A Descriptive Study in Provence-Alpes-Côte D'azur

Authors: Aida Habib, Anne-Claire Durand, Roland Sambuc, Franck Mazue and Stephanie Gentile

Abstract: To our knowledge, few studies in France have so far investigated the difference in patient characteristics and outcome between patients switching from hemodialysis (HD) to peritoneal dialysis (PD) and from DP to HD during treatment period. Therefore, the aim of the present retrospective study was to analyze main characteristics and outcome of switching patients and to identify risk factors that influence the outcome of switching patients.

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Research Article Pages 51-59

Testosterone Replacement Therapy (TRT) is Associated with Delayed Progression of Chronic Kidney Disease: A Retrospective Analysis of Testosterone Normalization in US Veterans

Authors: Rishi Sharma, MD, MHSA, Olurinde Oni, MBBS, MPH, Peter Wiegmann, BA, Mukut Sharma, PhD, Mariana Garcia-Touza, MD, Archana Goel, MD, Virginia Savin, MD, Rajat Barua, MD, PhD, Ram Sharma, MHSA, PhD, and Thomas Wiegmann, MD

Abstract: The aging male population suffers from late onset hypogonadism (LOH) with its characteristics including diminished virility, increased fatigue, muscle wasting and decreased bone mass. Fatigue, muscle wasting, and diminished libido are also common in advanced chronic kidney disease (CKD), with and without low testosterone. Testosterone deficiency is a common feature of failing kidneys and testosterone production is suppressed by multiple causes linked to loss of kidney function. Hypogonadism is the most common gonadal alteration in men

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Clinical Presentation Pages 47-50

Unmasking Nephrotic Syndrome

Authors: Mayleen Jeniffer L Laico

Abstract: A 65-year-old male was referred for nephrology consult for increasing creatinine from 1.7 mg/dl to 4.4 mg/dl over a period of 4 months. The patient was not diabetic but had a history of hypertension and dyslipidemia for which he was treated with amlodipine and atorvastatin respectively. He had noted increasing body malaise, weight loss, poor appetite and bipedal edema. He also noted frothy urine. On physical examination his blood pressure was 140/90 mmHg. He had pale palpebral conjunctivae and bipedal edema. The rest of the physical exam was unremarkable. Laboratory examinations were done at the time of consultation.

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