Vaccine Research and Development

Vaccine Research and Development

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Review Article Pages 9-15

Additional Doses of Vaccines against COVID-19 - Attempting to Enhance the Immune Response

Authors: Fernando Álvez

Abstract: Vaccination against COVID-19 with a complete primary series is essential. To date, COVID-19 vaccines have demonstrated high vaccine effectiveness against severe disease, hospitalization and death from COVID-19 in the majority of the properly vaccinated population. No vaccine including the COVID-19 vaccines is 100% effective so some breakthrough infections are possible. Moreover, evidence has been emerging of a "weakening" of immunity after passing the infection as well as a decrease in the effectiveness of the vaccines that have been administered against this infection. For this reason, according to many opinions, it will be necessary to reinforce the immune system through additional doses of the available vaccines.

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