Research Article

Efficacy and Safety of Sunitinib in Elderly Patients with Advanced Renal Cell Carcinoma at a University Hospital in Japan: Before Immuno-Oncology Therapy Era

Japan is a front-line country in the coming super-aging society. As with all cancers in the elderly, the frequency of renal cell carcinoma (RCC) is al... Read more

10.36959/896/599

Research Article

Artemisinin-dipeptidyl Vinyl Sulfone Hybrid Inhibitors of Plasmodium Falciparum Falcipain 2 with Favorable Pharmacokinetic Profile

In this work, we virtually design Artemisinin-Vinyl Sulfone Hybrid (AVSH) inhibitors of Falcipain2 (FP2) through Structure-Based Drug Design (SBDD) ap... Read more

10.36959/426/604

Review Article

Modelling of Desorption from Surface Effective Sites Formed on Nanosized Metal Clusters

It is found out that there are physical effects, typical of nanosized metal clusters deposited on a non-adsorbing support, that cause a difference bet... Read more

10.36959/672/588

Research Article

A Novel Nutrient Mixture Induces Apoptosis in Human Ovarian and Cervical Cancer Cells

Cervical cancer and ovarian cancer are the deadliest gynecological malignancies and are the fourth and fifth leading causes of death in women respecti... Read more

10.36959/749/520

Original Article

Solving Integer Programming Problems by Hybrid Bat Algorithm and Direct Search Method

The goal of this work is to suggest a new hybrid algorithm to solve integer programming by incorporating the bat algorithm with direct search methods.... Read more

10.36959/643/303

Review Article

Bacterial Biofilm and its Clinical Implications

Microbial biofilm created huge burden in treatment of both community and hospital infections. A biofilm is complex communities of bacteria attached to... Read more

10.36959/958/568

Review Article

Soils at the Altitudinal and Northern Treeline: European Alps, Northern Europe, Rocky Mountains - A Review

No treeline-specific soil types exist. The treeline ecotone is usually characterized by a mosaic of soil types closely related to the locally varying ... Read more

10.36959/948/463

Research Article

Embryo Rescue of Aged Cucurbita Pepo Seeds Using Squash Rescue Medium

Plant seed is both an important food source and an indispensable propagation material for many cultivated crop species. The ideal conditions required ... Read more

10.36959/745/399

Research Article

Pediatric Abdominal and Thoracic Equestrian Injuries-Single Center Experience

Recent years have witnessed an increase in the popularity of equestrian sports and therapeutic riding. The aim of the study was to report the prevalen... Read more

10.36959/472/348

Case Report

Fishing in the Dark: Retrieving Broken Instruments during a Spinal Lumbar Discectomy

The equipment utilized in surgical operations must be durable and safe. Regular checks to ensure no signs of wear or fatigue (that may result in failu... Read more

10.36959/765/392