Associate Professor
Molecular Medicine and Biomedical Engineering
Case Western Reserve University (BME)
United States of America
Tel: (216)-444-4326
Dr. Ramamurthi is an Associate Professor of Molecular Medicine and Biomedical Engineering at the Cleveland Clinic with a secondary appointment at Case Western Reserve University (BME). He received his PhD in Chemical Engineering, from Oklahoma State University (1999) and subsequently received an American Heart Association postdoctoral fellowship to pursue research at the Cleveland Clinic in developing novel glycosaminoglycan (GAG)-based biomaterials for biomimetic tissue engineering of aortic heart valves (1999-2001). Prior to his appointment at the Cleveland Clinic in 2010, Dr. Ramamurthi was a tenured faculty in the Departments of Bioengineering at Clemson University and Regenerative Medicine and Cell Biology the Medical University of South Carolina, Charleston, SC. His research program focuses on enabling biomimetic regeneration and repair of extracellular matrix structures, specifically the poorly regenerated elastic matrix component, both in vitro, and in situ at sites of chronic matrix disruption (e.g., abdominal aortic aneurysms or AAAs, and pelvic organ prolapse or POP). Current research projects in the Ramamurthi lab seek to a) develop stem cell and nanomedicine-based, non-surgical treatments for AAAs, POP, and non-small cell lung cancers (NSCLCs), b) identify new mechanistic targets for effecting regenerative matrix repair in proteolytic vascular diseases, c) design new biomaterials to promote endothelialization of vascular grafts, and d) investigate the peritoneal cavity as surrogate in vivo bioreactor systems to study in situ vascular tissue remodeling responses to biomaterial scaffolds. He is a member of several international professional societies in the cardiovascular sciences, biomaterials, and tissue engineering fields, and is a Professional Member of the American Heart Association Council on Arteriosclerosis, Thrombosis, and Vascular Biology. His research has been funded by the National Institutes of Health, National Science Foundation, American Heart Association (national and affiliate centers)and industry, and philanthropy.
