Dr. Gabriella Lupo is an Associate Professor of Biochemistry in the Department of Biochemical and Biotechnological Sciences of the University of Catania, Italy. Dr. Lupo completed his Ph.D in Biochemical and Biomolecular Sciences, Faculty of Medicine, University of Catania in the year 1995 and Postgraduate in Microbiology from same university in the year 1991. Dr. Gabriella Lupo research interest includes Studies of in vivo transport through the blood-brain and blood-retinal barrier, Role of the isoforms of phospholipase A2 in the processes of retinal and brain tumor angiogenesis, Effect of bacterial infections on the blood-brain/retinal barriers, Diabetic retinopathy and retinal angiogenesis, Studies of cell adhesion on biocompatible surfaces, Studies of intracellular signaling on human melanoma and retinoblastoma cell lines. Dr Lupo is currently working on diabetic retinopathy, major cause of vision loss, currently treated with anti-VEGF agents. High glucose impairs the retinal pericytes, surrounding endothelial cells, through activation of PLA2/COX-2/VEGF-A pathway.