Dr. Soldano Ferrone received his MD and PhD degrees in 1964 and in 1971, respectively, from the University of Milan, Milan, Italy. He has held faculty positions at the University of Milan, Scripps Clinic and Research Foundation, Columbia University, New York Medical College, Roswell Park Cancer Institute and at the University of Pittsburgh School of Medicine. Since 2012 he is a faculty member of the Department of Surgery at Massachusetts General Hospital, Harvard Medical School, Boston, MA. Dr. Ferrone has received many awards and honors. For the last 30 years he has been the member of many review committees including NIH Study Sections, and of the editorial boards of many scientific journals. Furthermore he is the member of several external scientific boards. Dr. Ferrone's research program focuses on the molecular characterization of escape mechanism(s) utilized by tumor cells to avoid immune recognition and destruction and on the development of combinatorial immunotherapeutic strategies to counteract the escape mechanism(s) utilized by tumor cells. These studies are greatly facilitated by the large panel of HLA antigen and human tumor antigen-specific monoclonal antibodies he has developed and shared with the scientific community over the years. Dr. Ferrone's research interests are HLA antigens, immunotherapy of malignant diseases, tumor immunology, immunoescape mechanisms.