ISSN: 2578-6512
Professor and Chair
Department of Biochemistry
University of Vermont Cancer Center
United States of America
Tel: 802-656-4874
Dr. Gary Stein is the Director of the University of Vermont Cancer Center and Chair of the University of Vermont College of Medicine Department of Biochemistry. Trained in Biology and Pathology. Dr. Stein has a longstanding dedication to basic, translational, and clinical cancer investigation. He has facilitated transdisciplinary institutional, regional, and global collaborative research initiatives with a priority for maximizing effectiveness of multi-center research programs and clinical trials. The central theme of his research has been to discover mechanisms controlling proliferation and differentiation emphasizing compromised genetic and epigenetic regulation linked with cancer. His focus is on mechanisms and biomarkers including non-coding RNAs associated with prostate, leukemia, breast, uterine and ovarian cancer prevention, early detection, treatment and survivorship. His lab characterizes genetic and epigenetic regulation that mediates cell cycle control and the abbreviated pluripotent cell cycle in human embryonic stem cells, induced pluripotent cells, and cancer stem cells. The Stein lab is investigating breast and prostate tumor metastasis to bone, including microRNA-mediated control, and is defining mechanisms that govern combinatorial organization and assembly of regulatory machinery in nuclear microenvironments, and epigenetic control of cell fate and lineage commitment in biological control and cancer. Dr. Stein has mentored more than 175 graduate students, research and clinical fellows and junior faculty. His research program is funded by program project grants and several RO1 grants as well as a long-term pharmaceutical company grant and foundation support. He has published more than 850 papers in leading biomedical journals and edited more than 20 books.
