Journal of Transplant Surgery

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Table of Content: Volume 1, Issue 1

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Research Article Pages 26-32

Long-Term Outcomes of Induction Therapies with Alemtuzumab, Basiliximab or Methylprednisolone in Kidney Transplant Patients with Delayed Graft Function

Authors: Allen Zhang, Beatrice Zhang, Yaozhong Liu, Mary Killackey, Anil Paramesh, Joseph Buell, Brent Alper, Fred Teran, Adrian Baudy and Rubin Zhang

Abstract: We compare the 5-year outcomes of induction therapies with methylprednisolone (n = 58), basiliximab (n = 56) or alemtuzumab (n = 98) in patients with DGF. Maintenance was tacrolimus and mycophenolate with prednisone in methylprednisolone and basiliximab groups or without prednisone in alemtuzumab group. Protocol biopsies were performed in all patients.

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Case Report Pages 23-25

Orthotopic Liver Transplantation for Treatment of Sinusoidal Obstruction Syndrome: A Case Report

Authors: Diego Quattrone, Thomas Schulz, Mathieu Gazon, Celine Guichon and Pr Frederic Aubrun

Abstract: We here report the case of successful orthotopic liver transplantation (LT) following acute liver failure (ALF) related to sinusoidal obstruction syndrome (SOS). This syndrome is one of the main causes of death early after bone marrow transplantation (BMT); LT seems to be an effective treatment of the most severe forms of SOS but no official recommendations exist about this subject. With this clinical case we would like to show that after careful patient selection and appropriate timing, LT for treatment of severe SOS is safe and effective.

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Research Article Pages 16-22

The Association between IMPDH II Gene 3757t > C and Ugt1a9 Gene T-275a Polymorphisms with Plasma Mycophenolic Acid among Renal Transplant Recipients

Authors: Ola Atef Sharaki, Mohamed Mostafa Mohamed rizk, Montasser Mohamed Zeid, Eman Saad Nassar and Iman Said Gharraf

Abstract: ESRD is a major health problem imposing great burden on the society. Dialysis either haemodialysis or peritoneal and transplantation are the two alternating treatment modalities. Transplantation became the preferred solution with lifetime monitoring immunosuppressive drugs.

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Review Article Pages 8-15

Crossmatch Strategies in Renal Transplantation: A Practical Guide for the Practicing Clinician

Authors: Nalaka Gunawansa, Roshni Rathore, Ajay Sharma and Ahmed Halawa

Abstract: Immunogenetic profiling of transplant recipients and pre-transplant tissue crossmatch between potential donor and recipient is mandatory in modern-day renal transplantation.

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Review Article Pages 1-7

Who Owns Hematopoietic Stem Cells? Some Fundamental Legal Stakes for the Manufacture of Cultured Red Blood Cells

Authors: Jean Mercier Ythier

Abstract: Significant R&D investment is currently being made in the design of cost-effective devices for the manufacture of red blood cells (RBCs) from hematopoietic stem cells. If successful, such techniques will permit the for-profit manufacture of homologous transfusion products for alloimmunized patients, at a supply price comparable to the cost of the phenotyped transfusion units currently in use.

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