Translational Neuroscience Research and Reviews

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Table of Content: Volume 2, Issue 1

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Research Article Pages 38-52

Effects of Non-Focused ELF-EMF Treatment on EEG: Preliminary Study

Authors: Alessandro Greco, MD and Alberto Garoli, MD

Abstract: The central nervous system (CNS) is known to be sensitive to focused magnetic stimulation, which is now used routinely for the treatment of various disorders. Extremely Low Frequency Electro Magnetic Fields (ELF-EMF) have been used in various clinical settings and tests however, to date, little is known regarding their functional mechanisms in vivo and, in particular, as a total-body non-focused administration.

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Research Article Pages 27-37

Transhemispheric Diaschisis after Unilateral Focal Cerebral Ischemia Reperfusion: A Longitudinal Voxel-Based Study by MRI

Authors: Saeid Taheri, PhD, Jin Yu, MD, Hong Zhu, MD, Honglian Shi, PhD and Mark S Kindy, PhD

Abstract: It is now little doubt that the insult of ischemia/reperfusion (I/R) impacts cerebral blood flow (CBF) not only within the lesion area but also in the area beyond the lesion territory. Focal I/R has been shown to impact the CBF dynamics even in the non-ischemic hemisphere. However, the quantitative transhemispheric CBF dynamics and its relationship to tissue microstructure changes following I/R has not been investigated.

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Review Article Pages 18-26

Common Substrates of Medication-Resistant Temporal Lobe Epilepsy: Hippocampal Sclerosis, Focal Cortical Dysplasia, and Combined Pathologies

Authors: Brandon M Korman, Ph.D, Psy D

Abstract: Temporal lobe epilepsy (TLE) is an etiologically heterogeneous syndrome that constitutes the largest proportion of refractory partial epilepsies. The most common substrates of TLE include focal cortical dysplasia (FCD) in children and hippocampal sclerosis (HS) in adults, with significant overlap of lesion types across age groups.

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Review Article Pages 10-17

Neuroprotective and Anti-Inflammatory Properties from the Bioactive Constituents of Myracrodruon Urundeuva, a Brazilian Medicinal Species

Authors: Glauce Socorro de Barros Viana and Iana Bantim Felício Calou

Abstract: Myracrodruon urundeuva Fr. All. (Anacardiaceae) is largely used, by the Northeast Brazil population, for its anti-inflammatory actions, already confirmed by experimental studies. In addition, this medicinal species presents neuroprotective properties, as demonstrated by in vitro and in vivo Parkinson's disease models. The trunk bark of M. urundeuva is a rich source of bioactive polyphenol compounds, as tannins and chalcones considered precursors of flavonoid biosynthesis.

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