Insights of Pharmacology and Pharmaceutical Science

Original Article Pages 9-17

Acute and Sub-chronic Toxicities of Aqueous and Ethanol Fruit Extracts of Solanum incanum Linn. in Male Swiss Albino Mice

Authors: Akanmu AO, Sandabe UK, Sodipo OA, Shamaki BU, Balogun ST and Jubrin J

Abstract: Solanum incanum Linn. (Solanaecae) is used for its medicinal and nutritional values in parts of tropical Africa, including Northeast of Nigeria. The present study evaluated acute and sub-chronic oral toxicities of S. incanum fruit extracts in Swiss albino mice. The fruits were extracted by cold maceration method using distilled water and ethanol as solvents. The acute toxicity studies of the aqueous and ethanol extracts were carried out using Lorke’s method.

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