Journal of Pediatric Neurology and Neuroscience

Original Article Pages 197-201

Focal Electrographic Hints in Epileptic Spasms

Authors: Mahmoud Mohammadi MD, Reza Shervin Badv, MD, Bahram Yarali, Safoura Kowkabi, Mahmoud Reza Ashrafi, Gholam Reza Zamani, Ali Reza Tavasoli, Mohsen Javadzadeh, Morteza Heidari, Mostafa Ghorbani and Zahra Rezaei MD

Abstract: Epileptic spasms (ES) is an age specific seizure disorder which is more frequent in infancy. Frequent untreated epileptic events have negative effect on development in ES patients so early diagnosis and appropriate treatments are key factors in management to avoid neurodevelopmental delay in survivors.

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Original Article Pages 131-133

Growing Skull Fracture [GSF], a Hydrodynamic Perspective: An Original Article

Authors: Allan J Drapkin, MD, FACS(R)

Abstract: Growing skull fracture (GSF) is a well-known complication of pediatric cranial trauma but its physiopathology has been, so far, only assumed. When the basic laws of hydraulics are applied to the underlying GSF pathology, a clearer understanding of the process involved in it emerges and accounts for the frequent spontaneous arrest of the skull erosion. Moreover the process causing the commonly associated intra-axial pathology is also better defined.

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Case Report Pages 125-130

Spontaneous Intracranial Hypotension Presenting with Chiari Malformation and Hydrocephalus Associated With Lumbar Pseudoarachnoiditis

Authors: Lacey M Carter, MD and Naina L Gross, MD

Abstract: Spontaneous intracranial hypotension (SIH) is a rare occurrence, especially in children. In the pediatric population, three cases of Chiari malformation in children and no cases of hydrocephalus due to SIH have been discussed in the literature. We present two patients under the age of five who presented with imaging concerning for the need for neurosurgical intervention later found to be due to SIH that resolved spontaneously.

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Case Report Pages 119-124

Mixed Nervous System Involvement in a Child with Multisystem Inflammatory Syndrome- A Rare Presentation of SARS-CoV-2

Authors: Aysha Fakhroo, Naveen Divakaran, Fareedul Hassan, Gabriel Fox, Imelda Lambert and Ahood Almuslamani

Abstract: Multi-system inflammatory syndrome (MIS-C) is a rare but severe complication of Covid-19 infection. The clinical presentation ranges from a mild course of systemic inflammatory response to a life threatening hyper inflammatory shock and multi organ dysfunction. Central nervous system presentation is seen in acute Covid-19 infection in adults but is rarely seen in children. We describe a case of MIS-C in a child who was admitted to our Pediatric Intensive

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Research Article Pages 110-118

Abusive Head Trauma in Infants and Children: Identifying Presenting Variables Associated With Outcome

Authors: Jessica L Carpenter, MD, Raquel Farias-Moeller, MD, Amy H Jones, MD, Shan Lateef, Abigail Ley, MD and Allison Jackson, MD, MPH

Abstract: We review 52 cases of presumed abusive head trauma (AHT) in children < 24 months of age admitted to a single center Pediatric Intensive Care Unit (PICU) between 2008 and 2017. Clinical variables were analyzed for association with neurological outcome ≥ 6 months post-injury using the Glasgow outcome score-extended for pediatrics (GOS-E Peds) and late seizures. Only patients with

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Review Article Pages 105-110

Hypothermia as an Adjunctive Treatment in Pediatric Patients with Naegleria fowleri: A Systematic Review

Authors: Archie Defillo, MD, Penelope E Nussbaum, Parvathy Hariharan, MS, Alexander Mebane, BS and Eric S Nussbaum, MD

Abstract: We reviewed the literature for pediatric patients infected with Naegleria fowleri (N. fowleri) to assess the relationship between patient survival and treatment with hypothermia. A systematic literature search was performed in PubMed to identify studies describing cases of pediatric N. fowleri infections. We identified 47 studies describing 55 pediatric patients

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Case Report Pages 99-104

Intracranial Mass Lesion Caused by Inflammatory Pseudotumor: A Case Report and Discussion

Authors: Andrew Reisner, MD, Matthew Schniederjan, MD, Joshua J Chern, MD, PhD, Andrew Appert, BS, Hannah E. Myers, BS. Psych, Barunashish Brahma, MD, Laura S Blackwell, PhD, William R Boydston, MD, PhD, and Sampath Prahalad, MD

Abstract: Inflammatory pseudo tumors are uncommon lesions that may, on occasion, occupy the intracranial space. Their management is unstandardized. We present a case of skull-based inflammatory pseudotumor in a 14-year-old boy who presented with multiple cranial nerve palsies mimicking Gradenigo syndrome. This illustrative case and a review of the literature is presented to highlight noteworthy features of this rare condition.

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Case Series Pages 95-98

Benign Neonatal Sleep Myoclonus in Uyo: Presentations, Diagnosis and Outcome

Authors: Eno Etim Nyong, MBBS, FWACP*, Mkpouto Udeme Akpan, MBBS, FWACP, Paulinus Umoren Essien, MBBS, FWACP and Itoro Anietimfon Akpan, MBBS, FWACP

Abstract: To describe four neonates with jerky movements of the limbs who were seen in University of Uyo Teaching Hospital between January 2014 to December 2018. They were all referred from other facilities for further management. The characteristics of the jerky movements were profiled and other confounding clinical states were excluded.

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Clinical Trial Pages 86-94

Modified Atkins Diet for Tics Requiring Treatment in Tourette Syndrome: A Randomized Controlled Trial of Early Versus Late Initiation

Authors: Camilla B Sørensen, MD, Liselotte Skov, MD, MSc, Lone Aaslet, NP, Helle Nielsen, RD, Mette Mortensen, RD, Theis Lange, PhD, Nanette Mol Debes, MD, PhD and Maria J Miranda, MD, PhD

Abstract: Increased dopamine activity is thought to play a role in the pathophysiology of Tourette syndrome (TS). Since ketogenic diet (KD) is thought to change several neurotransmitter systems, we hypothesized that modified KD could be beneficial in treatment of tics.

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Research Article Pages 84-85

How did Children with Complex Care Needs Affect during the Lockdown Due to the COVID-19 Pandemic?

Authors: V Mundada, T Gupta, A Pamfilo, A Joseph and S Banu

Abstract: The COVID-19 pandemic and the lockdown imposed by most of the governments because of it have affected most of us including children with complex care needs. Because of various reasons like changed routine and social isolation, the physical and psychological health of these children has affected. With this observational study, we tried to assess new symptoms with which children

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Journal of Pediatric Neurology and Neuroscience

Table of Content: Volume 5, Issue 1

Authors: Mahmoud Mohammadi MD, Reza Shervin Badv, MD, Bahram Yarali, Safoura Kowkabi, Mahmoud Reza Ashrafi, Gholam Reza Zamani, Ali Reza Tavasoli, Mohsen Javadzadeh, Morteza Heidari, Mostafa Ghorbani and Zahra Rezaei MD

Authors: Allan J Drapkin, MD, FACS(R)

Authors: Lacey M Carter, MD and Naina L Gross, MD

Authors: Aysha Fakhroo, Naveen Divakaran, Fareedul Hassan, Gabriel Fox, Imelda Lambert and Ahood Almuslamani

Authors: Jessica L Carpenter, MD, Raquel Farias-Moeller, MD, Amy H Jones, MD, Shan Lateef, Abigail Ley, MD and Allison Jackson, MD, MPH

Authors: Archie Defillo, MD, Penelope E Nussbaum, Parvathy Hariharan, MS, Alexander Mebane, BS and Eric S Nussbaum, MD

Authors: Andrew Reisner, MD, Matthew Schniederjan, MD, Joshua J Chern, MD, PhD, Andrew Appert, BS, Hannah E. Myers, BS. Psych, Barunashish Brahma, MD, Laura S Blackwell, PhD, William R Boydston, MD, PhD, and Sampath Prahalad, MD

Authors: Eno Etim Nyong, MBBS, FWACP*, Mkpouto Udeme Akpan, MBBS, FWACP, Paulinus Umoren Essien, MBBS, FWACP and Itoro Anietimfon Akpan, MBBS, FWACP

Authors: Camilla B Sørensen, MD, Liselotte Skov, MD, MSc, Lone Aaslet, NP, Helle Nielsen, RD, Mette Mortensen, RD, Theis Lange, PhD, Nanette Mol Debes, MD, PhD and Maria J Miranda, MD, PhD

Authors: V Mundada, T Gupta, A Pamfilo, A Joseph and S Banu