Journal of Pancreatic Cancer and Treatment

Review Article Pages 1-5

Pancreatic Cancer - The Role of Hypoxia

Authors: Katyayani Tatiparti, Kaustubh A Gawde, Hashem Alasab, Samaresh Sau, Sushil Kumar Kashaw, Prashant Kesharwani and Arun K Iyer

Abstract: Pancreatic cancer has very poor prognosis and has a very low five-year survival rate of the order of 5%. This is so because of the lack of major clinical symptoms and reliable detection markers. Recently, it has been realized that hypoxia is one of the major contributors to tumor growth, malignancy, invasion, propagation, metastasis, and resistance to therapy in several solid tumors including the pancreatic cancer.

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