Journal of Ophthalmic Research and Ocular Care

 ISSN: 2578-7160

Journal of Ophthalmic Research and Ocular Care

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Table of Content: Volume 1, Issue 1

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Review Article Pages 39-45

Myopia - A Brief Review. Investigation of +2 D. to +3 D. Reading Glasses to Prevent Myopia

Authors: Peter R Greene and Antonio Medina

Abstract: Basic control theory equations are developed showing classical exponential system response of refraction vs. time R(t), with a characteristic system time constant τ [100 days ± 20%] in response to a negative diopter (-) step change of the student's near-point reading environment.

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RESEARCH ARTICLE Pages 28-38

Loss of Displaced Starburst Amacrine Cells in a Rat Glaucoma Model

Authors: CA Cooley-Themm, Q Ameel, DM Linn and CL Linn

Abstract: Acetylcholine (ACh) release by starburst amacrine cells (SACs) has been implicated in the production of retinal waves during early retinal development. Inhibitory gamma-aminobutyric acid (GABA) release by SACs is known to be involved in directional selectivity in the mature retina.

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CASE REPORT Pages 25-27

Intraosseous Meningioma Mimicking Fibrous Dysplasia

Authors: Solomon S Shaftel, Ramzi M Alameddine, Sang-Rog Oh, Bobby S Korn, Jonathan H Lin and Don O Kikkawa

Abstract: Intraosseous meningiomas often display clinical and radiologic features that can be confused for fibrous dysplasia. Histopathology usually confirms the diagnosis. We present a case initially diagnosed as fibrous dysplasia by histopathology.

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Review Article Pages 19-24

Animal Models of Retinal Degeneration

Authors: Chung Yee Chung

Abstract: Retinal degenerations (RDs) are a vast and heterogeneous group of inherited degenerative diseases (dystrophies) of the retina that lead to progressive visual loss. The study of RDs involves animal models of various forms: from those naturally occurring to those genetically engineered, from insects to mammals.

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Editorial Pages 18

Neuropeptide Research in the Eye

Authors: Josef Troger

Abstract: The neuropeptide research in the eye began in the 80's with the investigation of the presence and distribution of substance P (SP), calciton in gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP) andneuropeptide Y (NPY). SP and CGRP have been found to be constituents of the sensory innervation of the eye whereas VIP can be attributed to the parasympathetic and NPY to the sympathetic innervation.

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Original Article Pages 12-17

Serum Homocysteine Levels in Patients with Retinal Vein Occlusion in a Spanish Population

Authors: Jose Luis Hernández, Marta Lisa, Jose Javier Napal, Ana Córdoba, Jose Manuel Olmos, Sheila Ruiz, Isabel Sierra and Romina García Sardina

Abstract: Prospective case-control study of all patients diagnosed with RVO at a tertiary-care hospital, and age-and sex-matched controls taking part in a population-based prospective cohort in the same geographic area. Differences in serum Hcy between both groups were analyzed by a general linear model adjusted for age, body mass index (BMI), glomerular filtration rate (GFR), hypertension, dyslipidemia, diabetes, tobacco use and alcohol intake.

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Review Article Pages 4-11

Mathematical and Numerical Methods for Modeling Drug Delivery to the Posterior Segment of the Eye

Authors: Paola Causin and Francesca Malgaroli

Abstract: The high incidence of diseases that affect the posterior segment of the eye (PSE)-here intended as composed by sclera, choroid and retina-prompts for establishing effective and well tolerated therapies. Topical application (instillation of drops) and systemic assumption remain the most widespread drug administration routes. However, the drug achieved levels are not therapeutically sufficient therapeutic, since in the first case the drug is mainly washed away by different pathways (aqueous humor, systemic adsorption, tears) and in the second reaches the PSE target in a minimal fraction.

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Case Report Pages 1-3

Bilateral Abducens Nerve Palsy due to Pseudotumor Cerebri in a Patient Taking Valproic Acid and Quetiapine: Report of a Case

Authors: Mualla Şahin Hamurcu, Fatma Sema Akkan Aydoğmuş, Murat Sinan Sarıcaoğlu, Ahmet Karakurt and Ufuk Hamurcu

Abstract: A 32-year-old overweight woman taking valproic acid and quetiapine because of bipolar disorder, admitted to the outpatient clinic with diplopia. She had not any other ophthalmic history. Ophthalmological examinations demonstrated esotropia in the left eye and papilledema in the both eyes. The abduction of both eyes was insufficient. CSF analysis revealed an extremely high pressure (28 mmHg) with normal CSF indices. These findings indicated that the patient had pseudotumor cerebri (PTC) that caused bilateral incomplete abducens nerve palsy with papilledema. The patient was discharged with oral acetazolamide therapy and three months after papilledema and abducens palsy were regressed.

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