Clinical Diabetes and Research

Case Report Pages 40-42

SGLT2 Inhibition May Precipitate Euglycemic DKA after Bariatric Surgery

Authors: Hassan Elasha, Ali Mekki Elsheikh, Wafic Wafa and Karim Meeran

Abstract: SGLT2 inhibitors (SGLT2Is) lower blood glucose through inhibition of glucose reabsorption in the proximal renal tubules via an insulin independent mechanism. They have a low risk of hypoglycaemia with additional benefits including weight loss, blood pressure reduction and cardiovascular protection [1]. Euglycaemic diabetic ketoacidosis (euDKA) is a rare complication of SGLT2Is observed in patients with both type 1 and type 2 diabetes and can be easily overlooked by medical care providers because of the absence of marked hyperglycaemia.

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