Journal of Brain Disorders

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Table of Content: Volume 3, Issue 1

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Research Article Pages 61-64

Immunotherapy for Glioma

Authors: Li Zhang, Xiao Qi Xie, Chen Yi and Feng Wang

Abstract: Glioma is the most common intracranial malignancy in the central system. At present, the treatment method of glioma is mainly surgical resection combined with chemotherapy and radiotherapy, but the malignancy degree of high-grade glioma is high, and the median survival period of patients is still short.

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Research Article Pages 47-60

Adult Vitamin D Deficiency Impairs Hippocampal- Dependent Memory and Proteins Related to Synaptic Plasticity and Metabolism in Mice

Authors: Natalie J Groves, Peter Josh, John J McGrath, Nyoman D Kurniawan and Thomas HJ Burne

Abstract: Vitamin D deficiency has been associated with a range of neuropsychiatric and neurodegenerative disorders, including schizophrenia, autism, depression, Alzheimer’s disease and cognitive impairment. The active form of vitamin D, 1,25(OH)2D3, is a neurosteroid that has a wide range of functions within the adult brain including calcium maintenance, regulation of neurotrophic factors, neurotransmission, and neuroprotection. Using a model of adult vitamin D (AVD) deficiency in BALB/c mice, we have previously shown an imbalance between excitatory and inhibitory neurotransmission,

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