Studies in Anatomy and Physiology

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Review Article Pages 5-12

Developmental Anomalies in Domestic Mammals and the One Health Concept

Authors: I Salazar

Abstract: Rudolf Virchow, considered by many the Father of Pathology, established a clear link between human and animal health. From that idea emerged the "one medicine" concept, which evolved into "one health" concept many years later.

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Review Article Pages 1-4

Gitelman Syndrome: What the Clinician Needs to know

Authors: Panagiotopoulou TV, Filippatos TD and Elisaf MS

Abstract: Gitelman syndrome has a prevalence of 1-10/40,000, representing the most common inherited disease of renal tubules. It is due to inactivating mutations of the SLC12A3 gene that encodes the thiazide-sensitive Sodium Chloride Cotransporter (NCC) located in the apical membrane of the distal convoluted tubules, resulting in hypokalemic metabolic alkalosis associated with hypomagnesemia and hypocalciuria.

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