Table 3: Comparison of PRA with CPRA.
| PRA | CPRA |
|---|---|
| Indicator of general non-specific reactivity between recipient and potential sample of donors |
Calculates specific unacceptable antigens in the wide donor database |
| Measures class-I and class-II antibodies separately | Class-I and class-II both calculated together |
| High PRA indicates high probability of positive crossmatch with a donor offer |
Even with a high CPRA, high probability of a negative crossmatch once the organ is offered |
| Variation in PRA based on laboratory and time of testing | No variation as it is based on a uniform database |