Table 1: Reported levels of the 45 Endocrine Disrupting Chemicals (EDCs) in human body fluids.
Endocrine Disrupting Chemicals (EDC) Adopted by the European Commission (EC) |
CAS RN |
Chemical Class |
Regulatory Status |
Reported levels of EDCs in Human Body Fluids (blood, plasma, umbilical cord fluid, etc.) or Urine* |
References |
Benzophenone-2; 2,2',4,4'- tetrahydroxybenzophenone |
131-55-5 |
Benzophenone |
Component Under Study |
0.05-0.07 ng/ml |
[17] |
Benzophenone-3; Oxybenzone |
131-57-7 |
Benzophenone |
Component Under Study |
60-140 ng/ml |
[20] |
Benzyl butyl phthalate; BBP |
85-68-7 |
Phthalate |
Sunset date, 02/21/2015 |
BDL (0.2 ng/mL) |
[14] |
3-Benzylidene camphor (3-BC); 1,7,7- trimethyl-3- (phenylmethylene)bicyclo[2.2.1]heptan-2- one |
15087-24-8 |
Camphor |
Component Under Study |
BDL |
[15] |
Bis(2-ethylhexyl) phthalate (DEHP) |
117-81-7 |
Phthalate |
Sunset date, 02/21/2015 |
103.55 ± 92.98 ng/ml |
[25] |
Bisphenol F |
620-92-8 |
Phenol |
Component Under Study |
212 ng/ml |
[23] |
Bisphenol S |
80-09-1 |
Phenol |
Component Under Study |
12.3 ng/ml |
[23] |
Butylated hydroxytoluene |
128-37-0 |
Phenol |
Component Under Study |
4.4-273.9 ng/g |
[28] |
Butylparaben; butyl 4-hydroxybenzoate |
94-26-8 |
Phenol |
Component Under Study |
0.03-0.42 ng/ml |
[18] |
Carbon disulphide |
75-15-0 |
Bisulphide |
Component Under Study |
BDL Very short half-life |
None |
Dibutyl phthalate (DBP) |
84-74-2 |
Phthalate |
Sunset date, 02/21/2015 |
0.18–13.47 µg/mL |
[27] |
Dicyclohexyl phthalate (DCHP) |
84-61-7 |
Phthalate |
Component Under Study |
BDL (0.2 ng/mL) |
[14] |
Diethyl phthalate (DEP) |
84-66-2 |
Phthalate |
Component Under Study |
0.64-3.11 µg/mL |
[27] |
Dihexyl phthalate (DHP) |
84-75-3 |
Phthalate |
Component Under Study |
BDL (0.2 ng/mL) |
[14] |
4,4'-Dihydroxybenzophenone |
611-99-4 |
Benzophenone |
Component Under Study |
BDL Very short half-life |
None |
Diisobutyl phthalate (DiBP) |
84-69-5 |
Phthalate |
Sunset date, 02/21/2015 |
BDL (0.2 ng/mL) |
[14] |
Diisodecyl phthalate (DiDP) |
26761-40-0 |
Phthalate |
Component Under Study |
BDL (0.2 ng/mL) |
[14] |
p-(1,1-Dimethylpropyl) phenol |
80-46-6 |
Phenol |
Component Under Study |
BDL Very short half-life |
None |
Dioctyl phthalate (DOP) |
117-81-7 |
Phthalate |
Sunset date, 02/21/2015 |
BDL (0.2 ng/mL) |
[14] |
Diundecyl phthalate (DuDP), branched and linear |
85507-79-5 |
Phthalate |
Component Under Study |
BDL (0.2 ng/mL) |
[14] |
2-Ethylhexyl 4-methoxycinnamate |
5466-77-3 |
Acrylate |
Component Under Study |
5-8 ng/ml |
[20] |
Ethylparaben |
120-47-8 |
Phenol |
Component Under Study |
0.02-31.7 ng/mL |
[80] |
4-Heptylphenol, branched and linear |
1987-50-4, 72624-02-3 |
Phenol |
Component Under Study |
BDL Very short half-life |
None |
Metam-sodium |
137-42-8 |
Dithiocarbamate |
Component Under Study |
BDL Very short half-life |
None |
3-(4-Methylbenzylidene) camphor; 1,7,7- trimethyl-3-[(4-methylphenyl) methylene]bicyclo[2.2.1] heptan-2-one |
36861-47-9 |
Camphor |
Component Under Study |
16-18 ng/ml |
[15] |
Methylparaben (MPB) |
99-76-3 |
Phenol |
Component Under Study |
43.9 ng/mL |
[24] |
4-Nitrophenol |
100-02-7 |
Phenol |
Component Under Study |
BDL Very short half-life |
None |
4-Nonylphenol, branched and linear |
- |
Phenol |
Component Under Study |
32 ng/mL |
[19] |
4-Nonylphenol, branched and linear, ethoxylated |
- |
Phenol |
Sunset date, 01/04/2021 |
0.07-0.16 ng/ml |
[19] |
Pentachlorophenol (PCP) |
87-86-5 |
Phenol |
Component Under Study |
109.6 ng/ml |
[26] |
Propylparaben; propyl 4-hydroxybenzoate |
94-13-3 |
Phenol |
Component Under Study |
2.9-60.4 ng/ml |
[81] |
Quadrosilan; 2,6-cis-Diphenylhexamethylcyclotetrasiloxane |
33204-76-1 |
Siloxane |
Component Under Study |
- |
None |
2,4-Dihydroxybenzophenone (Resbenzophenone) |
131-56-6 |
Benzophenone |
Component Under Study |
2.2-6.3 ng/ml |
[17] |
Resorcinol |
108-46-3 |
Phenol |
Component Under Study |
BDL |
[16] |
Tebuconazole |
107534-96-3 |
Triazole |
Component Under Study |
- |
None |
Tert-butylhydroxyanisole (BHA); tertbutyl-4-methoxyphenol |
25013-16-5 |
Phenol |
Component Under Study |
Very short half-life |
[82] |
Tert-butyl methyl ether; MTBE; 2- methoxy-2-methylpropane |
1634-04-4 |
Ether |
Component Under Study |
5-20 ng/ml |
[83] |
4-(1,1,3,3-Tetramethylbutyl)phenol |
140-66-9 |
Phenol |
Sunset date, 01/04/2021 |
0.2-20.6 ng/ml |
[19] |
4-(1,1,3,3-Tetramethylbutyl)phenol, ethoxylated |
- |
Phenol |
Component Under Study |
BDL Very short half-life |
None |
Thiram |
137-26-8 |
Dithiocarbamate |
Component Under Study |
BDL Very short half-life |
None |
2,4,6-Tribromophenol |
118-79-6 |
Phenol |
Component Under Study |
BDL Very short half-life |
None |
Triclosan |
3380-34-5 |
Phenol |
Component Under Study |
5.9 ng/ml |
[21] |
Triphenyl phosphate |
115-86-6 |
Phenol |
Component Under Study |
2.9 ng /ml |
[22] |
Zineb |
12122-67-7 |
Dithiocarbamate |
Component Under Study |
BDL Very short half-life |
None |
Ziram |
137-30-4 |
Dithiocarbamate |
Component Under Study |
BDL Very short half-life |
None |
*BDL Very short half-life means the ED is metabolized very rapidly and the parent compound was eliminated.