Table 1: Reported levels of the 45 Endocrine Disrupting Chemicals (EDCs) in human body fluids.

Endocrine Disrupting Chemicals (EDC) Adopted by the European Commission (EC)

CAS RN

Chemical Class

Regulatory Status

Reported levels of EDCs in Human Body Fluids (blood, plasma, umbilical cord fluid, etc.) or Urine*

References

Benzophenone-2; 2,2',4,4'- tetrahydroxybenzophenone

131-55-5

Benzophenone

Component Under Study

0.05-0.07 ng/ml

 [17]

Benzophenone-3; Oxybenzone

131-57-7

Benzophenone

Component Under Study

60-140 ng/ml

 [20]

Benzyl butyl phthalate; BBP

‎85-68-7

Phthalate

Sunset date, 02/21/2015

BDL (0.2 ng/mL)

 [14]

3-Benzylidene camphor (3-BC); 1,7,7- trimethyl-3- (phenylmethylene)bicyclo[2.2.1]heptan-2- one

15087-24-8

Camphor

Component Under Study

BDL

 [15]

Bis(2-ethylhexyl) phthalate (DEHP)

117-81-7

Phthalate

Sunset date, 02/21/2015

103.55 ± 92.98 ng/ml

 [25]

Bisphenol F

620-92-8

Phenol

Component Under Study

212 ng/ml

[23]

Bisphenol S

80-09-1

Phenol

Component Under Study

12.3 ng/ml

 [23]

Butylated hydroxytoluene

128-37-0

Phenol

Component Under Study

4.4-273.9 ng/g

 [28]

Butylparaben; butyl 4-hydroxybenzoate

‎94-26-8

Phenol

Component Under Study

0.03-0.42 ng/ml

 [18]

Carbon disulphide

75-15-0

Bisulphide

Component Under Study

BDL Very short half-life

None

Dibutyl phthalate (DBP)

84-74-2

Phthalate

Sunset date, 02/21/2015

0.18–13.47 µg/mL

 [27]

Dicyclohexyl phthalate (DCHP)

84-61-7

Phthalate

Component Under Study

BDL (0.2 ng/mL)

 [14]

Diethyl phthalate (DEP)

84-66-2

Phthalate

Component Under Study

0.64-3.11 µg/mL

 [27]

Dihexyl phthalate (DHP)

84-75-3

Phthalate

Component Under Study

BDL (0.2 ng/mL)

 [14]

4,4'-Dihydroxybenzophenone

611-99-4

Benzophenone

Component Under Study

BDL Very short half-life

None

Diisobutyl phthalate (DiBP)

84-69-5

Phthalate

Sunset date, 02/21/2015

BDL (0.2 ng/mL)

 [14]

Diisodecyl phthalate (DiDP)

26761-40-0

Phthalate

Component Under Study

BDL (0.2 ng/mL)

 [14]

p-(1,1-Dimethylpropyl) phenol

80-46-6

Phenol

Component Under Study

BDL Very short half-life

None

Dioctyl phthalate (DOP)

117-81-7

Phthalate

Sunset date, 02/21/2015

BDL (0.2 ng/mL)

 [14]

Diundecyl phthalate (DuDP), branched and linear

85507-79-5

Phthalate

Component Under Study

BDL (0.2 ng/mL)

 [14]

2-Ethylhexyl 4-methoxycinnamate

5466-77-3

Acrylate

Component Under Study

5-8 ng/ml

 [20]

Ethylparaben

‎120-47-8

Phenol

Component Under Study

0.02-31.7 ng/mL

 [80]

4-Heptylphenol, branched and linear

1987-50-4, 72624-02-3

Phenol

Component Under Study

BDL Very short half-life

None

Metam-sodium

137-42-8

Dithiocarbamate

Component Under Study

BDL Very short half-life

None

3-(4-Methylbenzylidene) camphor; 1,7,7- trimethyl-3-[(4-methylphenyl) methylene]bicyclo[2.2.1] heptan-2-one

36861-47-9

Camphor

Component Under Study

16-18 ng/ml

 [15]

Methylparaben (MPB)

99-76-3

Phenol

Component Under Study

43.9 ng/mL

 [24]

4-Nitrophenol

100-02-7

Phenol

Component Under Study

BDL Very short half-life

None

4-Nonylphenol, branched and linear

-

Phenol

Component Under Study

32 ng/mL

 [19]

4-Nonylphenol, branched and linear, ethoxylated

-

Phenol

Sunset date, 01/04/2021

0.07-0.16 ng/ml

 [19]

Pentachlorophenol (PCP)

87-86-5

Phenol

Component Under Study

109.6 ng/ml

 [26]

Propylparaben; propyl 4-hydroxybenzoate

94-13-3

Phenol

Component Under Study

2.9-60.4 ng/ml

 [81]

Quadrosilan; 2,6-cis-Diphenylhexamethylcyclotetrasiloxane

33204-76-1

Siloxane

Component Under Study

-

None

2,4-Dihydroxybenzophenone (Resbenzophenone)

131-56-6

Benzophenone

Component Under Study

2.2-6.3 ng/ml

 [17]

Resorcinol

108-46-3

Phenol

Component Under Study

BDL

 [16]

Tebuconazole

‎107534-96-3

Triazole

Component Under Study

-

None

Tert-butylhydroxyanisole (BHA); tertbutyl-4-methoxyphenol

25013-16-5

Phenol

Component Under Study

Very short half-life

 [82]

Tert-butyl methyl ether; MTBE; 2- methoxy-2-methylpropane

1634-04-4

Ether

Component Under Study

5-20 ng/ml

 [83]

4-(1,1,3,3-Tetramethylbutyl)phenol

140-66-9

Phenol

Sunset date, 01/04/2021

0.2-20.6 ng/ml

 [19]

4-(1,1,3,3-Tetramethylbutyl)phenol, ethoxylated

-

Phenol

Component Under Study

BDL Very short half-life

None

Thiram

137-26-8

Dithiocarbamate

Component Under Study

BDL Very short half-life

None

2,4,6-Tribromophenol

‎118-79-6

Phenol

Component Under Study

BDL Very short half-life

None

Triclosan

‎3380-34-5

Phenol

Component Under Study

5.9 ng/ml

 [21]

Triphenyl phosphate

115-86-6

Phenol

Component Under Study

2.9 ng /ml

 [22]

Zineb

‎12122-67-7

Dithiocarbamate

Component Under Study

BDL Very short half-life

None

Ziram

‎137-30-4

Dithiocarbamate

Component Under Study

BDL Very short half-life

None

*BDL Very short half-life means the ED is metabolized very rapidly and the parent compound was eliminated.