Table 1: Incidence and observed/expected ratio of Xeroderma Pigmentosum-associated malignancies [14-16].
|Malignancy||Incidence (all ages)||Observed/Expected (age < 20)||Observed/Expected (all ages)|
|Central Nervous System#||2%||50||33|
^Reported ocular malignancies include SCC, epithelioma/BCC, melanoma.
*Reported oral malignancies include SCC of the tongue apex, gingiva, and palate.
#Reported central nervous system malignancies include brain sarcoma and spinal cord astrocytoma.