Group

Route

Time

Mouse

1

Mouse 2

Mouse 3

Mouse 4

Mouse 5

Mouse 6

G1

IM

Before

5.74

6.03

5.67

5.45

5.49

5.37

G1

IM

After

5.95

6.07

6.44

6.01

6.31

6.08

G2

IV

Before

6.16

6.19

6.12

5.96

5.86

6.23

G2

IV

After

6.46

6.33

6.29

6.28

6.30

6.46

G3

SC

Before

5.53

5.98

5.81

6.04

5.68

5.66

G3

SC

After

6.14

6.13

6.09

6.32

6.24

6.37

G4

Topical

Before

6.06

5.82

5.70

5.81

5.40

6.20

G4

Topical

After

6.62

6.15

6.39

6.40

5.88

6.26

G5

Sublingual

Before

5.27

5.49

5.71

5.64

5.72

5.91

G5

Sublingual

After

6.13

6.19

6.97

5.81

6.20

6.40