Table 3: Classification of chronic kidney disease (CKD) risk categories based on the eGFR and dipstick ACR versus the eGFR and protein dipstick (≥ trace), protein dipstick (≥ 1+) or dipstick PCR (≥ 150 mg/g).
|
eGFR and ACR-based |
|||||
|
Low risk CKD |
Moderately increased risk |
High risk |
Very high risk |
Total |
|
|
N (%) |
N (%) |
N (%) |
N (%) |
N (%) |
|
|
eGFR and protein dipstick ( ≥ trace) |
|||||
|
Low risk CKD |
70,639 (81.7) |
4,181 (4.84) |
648 (0.75) |
0 (0) |
75,468 (87.29) |
|
Moderately increased risk |
566 (0.65) |
4,908 (5.68) |
348 (0.4) |
38 (0.04) |
5,860 (6.78) |
|
High risk |
1,103 (1.28) |
2,421 (2.8) |
903 (1.04) |
47 (0.05) |
4,474 (5.17) |
|
Very high risk |
0 (0) |
112 (0.13) |
251 (0.29) |
292 (0.34) |
655 (0.76) |
|
Total |
72,308 (83.63) |
11,622 (13.44) |
2,150 (2.49) |
377 (0.44) |
86,457 (100) |
|
Kappa (95% CI) |
0.567 (0.560, 0.574) |
||||
|
Concordance rate* |
88.76% |
||||
|
eGFR and protein dipstick (≥ 1+) |
|||||
|
Low risk CKD |
71,205 (82.36) |
5,127 (5.93) |
708 (0.82) |
0 (0) |
77,040 (89.11) |
|
Moderately increased risk |
1091 (1.26) |
6,177 (7.14) |
755 (0.87) |
39 (0.05) |
8,062 (9.32) |
|
High risk |
12 (0.01) |
314 (0.36) |
632 (0.73) |
119 (0.14) |
1,077 (1.25) |
|
Very high risk |
0 (0) |
4 (0) |
55 (0.06) |
219 (0.25) |
278 (0.32) |
|
Total |
72,308 (83.63) |
11,622 (13.44) |
2,150 (2.49) |
377 (0.44) |
86,457 (100) |
|
Kappa (95% CI) |
0.607 (0.600, 0.614) |
||||
|
Concordance rate* |
90.48% |
||||
|
eGFR and PCR-based |
|||||
|
Low risk CKD |
71,268 (82.43) |
4,199 (4.86) |
648 (0.75) |
0 (0) |
76,115 (88.04) |
|
Moderately increased risk |
1,027 (1.19) |
6,954 (8.04) |
376 (0.43) |
38 (0.04) |
8,395 (9.71) |
|
High risk |
13 (0.02) |
467 (0.54) |
1,088 (1.26) |
57 (0.07) |
1,625 (1.88) |
|
Very high risk |
0 (0) |
2 (0) |
38 (0.04) |
282 (0.33) |
322 (0.37) |
|
Total |
72,308 (83.63) |
11,622 (13.44) |
2,150 (2.49) |
377 (0.44) |
86,457 (100) |
|
Kappa (95% CI) |
0.683 (0.676, 0.689) |
||||
|
Concordance rate* |
92.06% |
||||
*Agreement of CKD categories between ACR- and proteinuria-based classifications. Data are N (%) values except where indicated otherwise.
eGFR: estimated Glomerular filtration rate; ACR: Albumin-to-creatinine ratio; PCR: Protein-to-creatinine ratio; CI: Confidence interval.