Table 1: LD50 and toxic signs manifested following oral and intraperitoneal administration of aqueous and ethanol fruit extracts of S. incanum.

Extract

Route

Toxic Sign

*Minimum Dose (mg/kg)

LD50(mg/kg)

Aqueous extract

Oral

Restlessness, writhing, increased breathing, tremor

5000

3808

intraperitoneal

Restlessness, writhing, increased breathing, tremor

370

288.5

Ethanol extract

Oral

None

-

> 5000

intraperitoneal

Restlessness, writhing, increased breathing, tremor

370

288.5

*Minimum dose that produced toxic sign