Table 1: LD50 and toxic signs manifested following oral and intraperitoneal administration of aqueous and ethanol fruit extracts of S. incanum.
Extract |
Route |
Toxic Sign |
*Minimum Dose (mg/kg) | LD50(mg/kg) |
Aqueous extract |
Oral |
Restlessness, writhing, increased breathing, tremor |
5000 |
3808 |
intraperitoneal |
Restlessness, writhing, increased breathing, tremor |
370 |
288.5 |
|
Ethanol extract |
Oral |
None |
- |
> 5000 |
intraperitoneal |
Restlessness, writhing, increased breathing, tremor |
370 |
288.5 |
*Minimum dose that produced toxic sign