Table 3: Secondary outcomes.

Period 1 Period 2 P-value 95% confidence interval
Control group Treatment group
No probiotics Infloran
(N = 297) (N = 283)
Time to establish feeds (days)
- 50 mls/kg/d (median, IQR 25-75%) 5 (4-7) 5 (4-8) 0.31 -
- 100 mls/kg/d (median, IQR 25-75%) 7 (5-10) 7 (5-10) 0.15 -
- 150 mls/kg/d (median, IQR 25-75%) 8 (7-11.75) 9 (7-12) 0.32 -
Time to regain birth weight (days)
- (median, IQR 25-75%) 12 (9-16) 11 (8-14) 0.03 0.08-1.69
Parenteral nutrition
- Infants requiring parenteral nutrition (%) 193 (65.0) 191 (67.5) 0.52 -
- Duration of parenteral nutrition (days) 9 (7-13) 9 (7-12) 0.48 -
Central lines
- UVC (%) 125 (42.1) 132 (46.6) 0.27 -
- Duration UVC (days) (median, IQR 25-75%) 6 (4-8) 6 (4-8) 0.84 -
- PICC line (%) 146 (49.2) 149 (52.7) 0.40 -
- Duration PICC lines (days) (median, IQR 25-75%) 8 (7-13) 8 (6-13) 0.58 -
Duration of hospitalization
- (median, IQR 25-75%) 58 (40.25-80.75) 57 (41-78) 0.89 -

UVC = Umbilical Venous Catheter; PICC line = Peripherally Inserted Central Catheter.