Table 1: Clinical features of the patient in this case report compared to previously reported Dias-Logan syndrome patients.
Clinical features |
Eleven patients described by Dias, et al. [1] |
The patient in this case report |
Abnormal external ears |
5/8 |
+ |
Autism spectrum disorder |
3/10 |
Likely |
Behavior problems |
6/9 |
+ |
Blue sclerae in infancy |
4/8 |
- |
Down-slanting palpebral fissures |
4/8 |
- |
Everted lower face |
6/8 |
- |
Flat midface |
6/8 |
- |
Global developmental delay/intellectual disability |
10/10 |
+ |
Joint hypermobility |
7/8 |
- |
Language delay |
10/10 |
+ |
Microcephaly |
5/9 |
+ |
Strabismus |
8/8 |
+ |
Thin upper lip |
7/8 |
- |
Legend: + represents the presence of clinical feature; - represents the absence of clinical feature; "likely" means the patient displays many signs of autism, but an official evaluation has not yet been completed