Author

Patient Age (yrs)/Sex

Pharmaceutical Management

Administered

Treatment

Outcome

Cope, et al., 2016 [10]

12/M

amphotericin B, azithromycin, dexamethasone, fluconazole, miltefosine, rifampin

Surgical decompression, hypertonic saline and mannitol, induced hypothermia (no description)

Brain death

Linam, et al., 2015 [7]; Dunn, et al., 2016 [8]; Heggie, et al., 2017 [9]

12/F

amphotericin B, azithromycin, dexamethasone, fluconazole, hyperosmolar therapy, miltefosine, rifampin

External ventricular drain, CSF drainage, moderate hyperventilation, induced hypothermia (32-34 °C) in the management of PAM

Full neurologic recovery; cerebral edema resolved after using hypothermia in conjunction with other therapies

Stowe, et al., 2017 [11]

14/M

amphotericin B, azithromycin, ceftriaxone, fluconazole, miltefosine, pentobarbital, rifampin, vancomycin

Induced hypothermia (no description)

Death