Table 1: Overview of key information.

 

Patient 1

Patient 2

Patient 3

Patient 4

Age at diagnosis

51

30

52

26

Sex

Male

Male

Male

Male

Presenting symptoms

Headaches; blurry vision; photophobia; diminished libido/spontaneous erections

Visual field deficits; blurry vision; headaches; diminished libido

Headaches; diminished libido/spontaneous erections

Headaches; vision loss; fatigue; diminished libido

Tumor size at diagnosis (AP × CC × TV) [cm]

3.7 × 5.4 × 2.9

2.5 × 3.5

4.5 × 5.2 × 4.8

2.0 × 3.4 × 2.2

Tumor size pre-operatively (AP × CC × TV) [cm]

3.7 × 4.1 × 2.7

2.6 × 3.3 × 3.0

4.4 × 5.6 × 5.5

 -

Duration of cabergoline treatment (months)

1

6

2

0

Amount of tumor fibrosis (%)

60-70

50-60

50-60

15

Patient outcomes

Symptom improvement; PRL normalization; GTR

Symptom improvement; STR

Symptom improvement; initial PRL normalization, followed by PRL elevation

Symptom improvement; no PRL normalization; GTR

Post-operative cabergoline advised?

No

No

Yes*

Yes

Lost to follow-up?

Yes

Yes

Yes

Yes

AP: Anterior-Posterior; CC: Cranio-Caudal; TV: Transverse; PRL: Prolactin; ✢: Full dimensions were unavailable as scans were completed at an outside institution; *: Patient was lost to follow-up before cabergoline was provided