According to a recent publication by Andre´s, et al., 2020, PTC-CCV is histologically characterized by these features [10].

Table 1: According to a recent publication by Andre´s, et al., 2020, PTC-CCV is histologically characterized by these features [10].

Clinical features	Histological features	Molecular features
Infiltrative form with extrathyroid extension: Rapid growth rate Local invasion Early lymph node metastasis High rate of recurrences 5^th-6^th decade of life Encapsulated form minimally invasive: high cure rate	Columnar cells with pseudostratified nuclei and no eosinophilic cytoplasm Hypercellular neoplasm with thin papillae and glandular structures Nuclear features of papillary carcinoma not as well developed as classic PTC Occasional subnuclear vacuolization or even clear cytoplasm	BRAFV600E (33%)