Table 2: Histopathologic features of needle core biopsies with an elevated IgG+:total plasma cells ratio1.
| Clinical diagnosis | IgG4RD | Unknown etiology | HCV | HPV |
|---|---|---|---|---|
| Plasma cells/5 HPF (average) | 140 | 48 | 2 | 7 |
| IgG4+ plasma cells/5 HPF (average) | 97 | 25 | 1 | 3 |
| IgG4+ plasma cells:total plasma cells | 69% | 52% | 50% | 43% |
| Eosinophils/5 HPF (average) | 7 | 55 | 14 | 19 |
1Significant increase was defined as ≥ 40%. HCV: Chronic Hepatitis C; HPF: High Power Field; IgG: Immunoglobulin G; IgG4RD; Immunoglobulin G4-related disease.