Table 4: Confidence intervals and the amount of change between the 25% and 75% points.

 Factor

Low

High

Effect

95% CI

n = 518

Sex (woman)

1

2

-22.499

-50.369

to

5.370

 

Age (years)

41

67

-14.194

-34.897

to

6.510

 

Hypertension (yes)

1

2

-1.795

-34.802

to

31.210

 

Asthma (yes)

1

2

-16.839

-45.474

to

11.800

 

Antithrombotic medication (yes)

1

2

-29.816

-81.885

to

22.250

 

Smoking habit (yes)

2

1

-7.467

-30.480

to

15.540

 

Alcohol consumption (yes)

2

1

1.397

-20.963

to

23.760

 

Preoperative sBP (mmHg)

109

136

0.195

-21.182

to

21.570

 

Preoperative dBP (mmHg)

65

85

-2.961

-8.194

to

2.270

 

Sinus disease (vs. CRSw/sNP)

             

Odontogenic maxillary sinusitis

5

2

29.396

-9.074

to

67.870

 

Fungal sinusitis

5

4

36.686

-4.150

to

77.520

 

Cystic disease

5

3

-17.183

-75.246

to

40.880

 

Eosinophillic chronic rhinosinuitis

5

1

13.456

-25.046

to

51.960

 

Number of inflamed sinuses (pieces)

0

10

-18.759

-73.544

to

36.030

 

Lund Mackay score (points)

5

14

73.047

38.151

to

107.940

 

Nasal polyps (yes)

2

1

-1.807

-28.706

to

25.090

 

Preoperative macrolide dose (yes)

1

2

1.688

-21.209

to

24.590

 

Preoperative steroid dose (yes)

1

2

-13.475

-48.361

to

21.410

 

Operative time (minutes)

102

201

28.229

8.013

to

48.450

 

Initial surgery or re-operation (Initial)

1

2

49.098

18.268

to

79.930

 

Unilateral or bilateral (bilateral)

2

1

0.689

-40.976

to

42.350

 

Number of sinuses opened (pieces)

4

10

13.561

-32.971

to

60.090

 

WBC (/μl)

5100

7293

15.407

-0.199

to

31.010

 

Neu/Lym ratio

1.00

2.449

1.412

-7.369

to

10.190

 

Eos (%)

1.00

6.400

-6.272

-17.604

to

5.060

 

Hb (g/dl)

13.00

15.100

7.846

-12.708

to

28.400

 

Plt (10^4/μl)

19.00

27.375

-12.013

-27.455

to

3.430

 

Alb (g/dl)

4.00

4.700

-6.727

-21.897

to

8.440

 

AST (U/L)

18.00

27.000

-0.124

-13.818

to

13.570

 

ALT (U/L)

13.00

28.750

3.407

-16.244

to

23.060

 

γGTP (U/L)

16.00

42.000

-2.198

-12.956

to

8.560

 

ALP (U/L)

185.00

278.750

-3.685

-11.661

to

4.290

 

T-bil (mg/dl)

0.00

0.800

-4.553

-12.530

to

3.420

 

Creatinine (mg/dl)

0.00

0.860

-0.199

-4.360

to

3.960

 

CRP (mg/dl)

0.00

0.223

-0.548

-3.346

to

2.250

 

PT-INR

0.00

1.020

5.839

0.117

to

11.560

 

APTT (seconds)

28.00

1.020

5.809

-4.135

to

15.750

 

The four main items that showed significant differences were as follows: an increase of 1 in PT-INR at 64.9 mL, increase in the Lund Mackay score from 5 to 14 points at 73.0 mL, increase in operative time from 102 to 201 min to 28.2 mL, and the frequency of re-operation increased compared to initial surgery at 49.1 mL.
sBP: systolic Blood Pressure; dBP: diastolic Blood Pressure; CRS: Chronic Rhinosinusitis; WBC: White Blood Cell; Neu/Lym ratio: Neutrophil/Lymphocyte; Eos: Eosinophils; Hb: Haemoglobin; Plt: Platelet; Alb: Albumin; AST: Aspartate Aminotransferase; ALT: Alanine Aminotransferase; γ-GTP: γ-Glutamyl Transpeptidase; ALP: Alkaline Phosphatase; T-bil: Total Bilirubin; CRP: C-Reactive Protein; PT-INR: Prothrombin Time-International Normalised Ratio; APTT: Activated Partial Thromboplastin Time