Table 3: Results of multivariate analysis by linear regression.
|
Factor |
Estimate |
Standardized |
Std. Error |
Pr(>|t|) |
n = 518 |
|
Sex (woman) |
-22.499 |
-0.085 |
14.183 |
0.11 |
|
|
Age (years) |
-0.551 |
-0.076 |
0.409 |
0.18 |
|
|
Hypertension (yes) |
-1.795 |
-0.0062 |
16.798 |
0.91 |
|
|
Asthma (yes) |
-16.839 |
-0.057 |
14.573 |
0.25 |
|
|
Antithrombotic medication (yes) |
-29.816 |
-0.049 |
26.499 |
0.26 |
|
|
Smoking habit (yes) |
7.467 |
0.030 |
11.711 |
0.52 |
|
|
Alcohol consumption (yes) |
-1.397 |
-0.0056 |
11.379 |
0.90 |
|
|
Preoperative sBP (mmHg) |
0.0072 |
0.0011 |
0.403 |
0.99 |
|
|
Preoperative dBP (mmHg) |
-0.148 |
-0.047 |
0.133 |
0.27 |
|
|
Sinus disease |
|||||
|
Odontogenic maxillary sinusitis |
15.940 |
0.041 |
27.463 |
0.56 |
|
|
Fungal sinusitis |
23.230 |
0.057 |
28.232 |
0.41 |
|
|
Cystic disease |
-30.639 |
-0.052 |
35.002 |
0.38 |
|
|
CRS with/without nasal polyps |
-13.456 |
-0.053 |
19.594 |
0.49 |
|
|
Number of inflamed sinuses (pieces) |
2.260 |
0.054 |
3.947 |
0.57 |
|
|
Lund Mackay score (points) |
-8.116 |
0.385 |
1.973 |
＜0.0001 |
*** |
|
Nasal polyps (yes) |
1.807 |
0.0071 |
13.690 |
0.90 |
|
|
Preoperative macrolide dose (yes) |
1.688 |
0.0063 |
11.653 |
0.88 |
|
|
Preoperative steroid dose (yes) |
-13.475 |
-0.035 |
17.754 |
0.45 |
|
|
Operative time (minutes) |
0.286 |
0.145 |
0.104 |
0.0063 |
** |
|
Initial surgery or re-operation (re) |
49.098 |
0.150 |
15.690 |
0.0019 |
** |
|
Unilateral or bilateral (bilateral) |
-0.689 |
-0.0027 |
21.204 |
0.97 |
|
|
Number of sinuses opened (pieces) |
-2.680 |
-0.072 |
3.983 |
0.50 |
|
|
WBC (/μl) |
0.0070 |
0.096 |
0.004 |
0.05 |
|
|
Neu/Lym ratio |
1.321 |
0.015 |
4.181 |
0.75 |
|
|
Eos (%) |
-1.364 |
-0.052 |
1.254 |
0.28 |
|
|
Hb (g/dl) |
4.185 |
0.045 |
5.579 |
0.28 |
|
|
Plt (10^4/μl) |
-1.586 |
-0.075 |
1.038 |
0.13 |
|
|
Alb (g/dl) |
-16.818 |
-0.045 |
19.300 |
0.38 |
|
|
AST (U/L) |
-0.014 |
-0.0013 |
0.774 |
0.99 |
|
|
ALT (U/L) |
0.216 |
0.026 |
0.635 |
0.73 |
|
|
γGTP (U/L) |
-0.085 |
-0.020 |
0.211 |
0.69 |
|
|
ALP (U/L) |
-0.039 |
-0.040 |
0.043 |
0.36 |
|
|
T-bil (mg/dl) |
-22.763 |
-0.051 |
20.299 |
0.26 |
|
|
Creatinine (mg/dl) |
-0.906 |
-0.004 |
9.626 |
0.93 |
|
|
CRP (mg/dl) |
-3.138 |
-0.019 |
8.147 |
0.70 |
|
|
PT-INR |
64.883 |
0.090 |
32.356 |
0.046 |
* |
|
APTT (seconds) |
1.298 |
0.049 |
1.131 |
0.25 |
|
Significant (p < 0.05) differences were observed in PT-INR, Lund-Mackay score, operative time, and initial surgery versus re-operation. No significant differences were found for the other items.
sBP: systolic Blood Pressure; dBP: diastolic Blood Pressure; CRS: Chronic Rhinosinusitis; WBC: White Blood Cell; Neu/Lym ratio: Neutrophil/Lymphocyte; Eos: Eosinophils; Hb: Haemoglobin; Plt: Platelet; Alb: Albumin; AST: Aspartate Aminotransferase; ALT: Alanine Aminotransferase; γ-GTP: γ-Glutamyl Transpeptidase; ALP: Alkaline Phosphatase; T-bil: Total Bilirubin; CRP: C-Reactive Protein; PT-INR: Prothrombin Time-International Normalised Ratio; APTT: Activated Partial Thromboplastin Time
*p < 0.05; **p < 0.01; ***p < 0.001