Table 1

Table 1

S No	Year	Study	Title	Medicine used	Type of Study	Results
1	2011	Moslemi, Mousavi Jazi, et al. (2011)	“Acellular dermal matrix allograft versus subepithelial connective tissue graft in treatment of gingival recessions: A 5-year randomized clinical study.“	The study compared two surgical techniques for the treatment of gingival recessions: No specific medicine was mentioned in the study.	Randomized trial.	Throughout a 5-year period, it was discovered that subepithelial connective tissue graft (SCTG) and acellular dermal matrix allograft (ADMA) were both successful in treating gingival recessions..
2	2012	Jimi, Hirata, et al. (2012)	“The current and future therapies of bone regeneration to repair bone defects. International journal of dentistry, 2012.”	Not any specific medicine used for bone regeneration in this study. It provides a review of bone regeneration to repair bone defects, including various surgical techniques and materials such as bone grafts, growth factors, and stem cells.	Literature review.	The article provides a comprehensive review of bone regeneration to repair defects, including various surgical techniques and materials such as bone grafts, growth factors, and stem cells.
3	2014	Benic and Hämmerle (2014)	“Horizontal bone augmentation by means of guided bone regeneration.”	In this study specific medicine used for horizontal bone augmentation. It discusses the use of guided bone regeneration (GBR) technique for horizontal bone augmentation.	Literature review.	The study demonstrates the effectiveness of guided bone regeneration (GBR) technique in horizontal bone augmentation.
4	2014	Faverani, Ramalho-Ferreira, et al. (2014)	“Surgical techniques for maxillary bone grafting-literature review.”	This study does not discuss any specific medicine used discussed various surgical techniques for maxillary bone grafting.	Literature review.	The article provides a literature review of various techniques for bone grafting
5	2015	Khojasteh, A., Esmaeelinejad, M., & Aghdashi, F. (2015)	“Regenerative techniques in oral and maxillofacial bone grafting.”	The research paper discusses regenerative medicine techniques used in oral and maxillofacial bone grafting, stem cells, and tissue engineering. These techniques aim to enhance bone regeneration and improve patient outcomes.	Review article.	It provides an overview of existing research on regenerative techniques in oral and maxillofacial bone grafting. The article discusses the benefits and limitations of different regenerative approaches, as well as their clinical applications and outcomes.
6	2015	(Faverani, et al., 2014)	“Simple bone augmentation for alveolar ridge defects.”	The research paper discusses various bone augmentation techniques used to address alveolar ridge defects.	Review article.	The study does not present new results. Instead, it provides an overview of various bone augmentation techniques used to address alveolar ridge defects, The article discusses the advantages and disadvantages of each technique, as well as their clinical applications and outcomes.
7	2016	Sharif, F., Rehman, I. U., Muhammad, N., & MacNeil, S. (2016)	“Dental materials for cleft palate repair.”	The study discusses various dental materials used for cleft palate repair. It does not focus on a specific medicine, but rather on the types of materials used for this purpose, such as bone grafts, dental adhesives, and composite materials.	Review article.	It provides an overview of various dental materials used for cleft palate repair, including bone grafts, dental adhesives, and composite materials. The article discusses the properties and applications of each material, as well as their advantages and disadvantages for cleft palate repair.
8	2017	Motamedian, S. R., Tabatabaei, F. S., Akhlaghi, F., Torshabi, M., Gholamin, P., & Khojasteh, A. (2017)	“Response of Dental Pulp Stem Cells to Synthetic, Allograft, and Xenograft Bone Scaffolds.”	The study investigates the response of dental pulp stem cells to synthetic, allograft, and xenograft bone scaffolds. The medicine used in this study is not applicable since the study focuses on different types of bone scaffolds used for dental pulp stem cell regeneration.	Original research.	The study found that dental pulp stem cells (DPSCs) can attach and proliferate on synthetic, allograft, and xenograft bone scaffolds. However, the DPSCs on the synthetic scaffolds had the highest proliferation rate, while those on the allograft and xenograft scaffolds had a slower rate of proliferation. The study also found that the DPSCs on the synthetic scaffold had higher expression levels of bone-specific markers than those on the allograft and xenograft scaffolds. These findings suggest that synthetic bone scaffolds may be a promising option for DPSC-based bone regeneration therapies.
9	2018	Yamada, M., & Egusa, H. (2018)	“Current bone substitutes for implant dentistry.”	The study reviews various types of bone substitutes used in implant dentistry, including autografts, allografts, xenografts, and synthetic bone substitutes. The medicine used in this study is not applicable since it is a review article.	Review article.	It provides an overview of various types of bone substitutes used in implant dentistry, including autografts, allografts, xenografts, and synthetic bone substitutes. The article discusses the advantages and disadvantages of each type of bone substitute, as well as their clinical applications and outcomes.
10	2019	Bracey, D. N., Seyler, T. M., Jinnah, A. H., Smith, T. L., Ornelles, D. A., Deora, R & Whitlock, P. W. (2019)	“A porcine xenograft‐derived bone scaffold is a biocompatible bone graft substitute: an assessment of cytocompatibility and the alpha-Gal epitope.”	The study assesses the biocompatibility of a porcine xenograft-derived bone scaffold for use as a bone graft substitute. The medicine used in this study is the porcine xenograft-derived bone scaffold.	original research article	The study found that the porcine xenograft-derived bone scaffold showed good cytocompatibility and did not elicit a significant immune response related to the alpha-Gal epitope. The scaffold also promoted osteoblast differentiation and bone formation, suggesting that it may be a promising bone graft substitute.
11	2019	Moy, P. K., & Aghaloo, T. (2019)	“Risk factors in bone augmentation procedures.”	The study does not use any medicine as it is a review article that discusses risk factors associated with bone augmentation procedures.	Review article.	The study provides an overview of the risk factors associated with bone augmentation procedures, including patient factors, surgical factors, and implant factors. The article discusses the impact of these risk factors on the success of bone augmentation procedures and offers recommendations for minimizing their effects.
12	2022	Manfio, A. S. C., Suri, S., Dupuis, A., & Stevens, K. (2022)	“Eruption path of permanent maxillary canines after secondary alveolar bone graft in patients with nonsyndromic complete unilateral cleft lip and palate.”	The medicine used in the study is not applicable as the study involves a surgical procedure for bone grafting in the alveolar ridge.	Original research article.	The study found that secondary alveolar bone grafting can improve the eruption path of the permanent maxillary canines in patients with complete unilateral cleft lip and palate. The study suggests that this procedure can help prevent impaction and improve the alignment of the canines, leading to better dental function and esthetics.
13	2021	Zhao, R., Yang, R., Cooper, P. R., Khurshid, Z., Shavandi, A., & Ratnayake, J. (2021)	“Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments.”	The study primarily focuses on the medicine used in dentistry, such as different types of bone grafts and substitutes. The article reviews various types of materials used in dentistry, such as autogenous bone grafts, allografts, xenografts, and synthetic bone substitutes.	Review article.	The results of the study indicate that there have been significant advancements in the development of bone grafts and substitutes, which have improved the success rates of dental implantology and periodontal surgery. The authors discuss the advantages and disadvantages of each type of bone graft material, as well as the limitations and future directions of research in this field. Overall, the study provides valuable insights into the current trends and developments in bone grafts and substitutes in dentistry.
14	2020	Tahmasebi, E., Alam, M., Yazdanian, M., Tebyanian, H., Yazdanian, A., Seifalian, A., & Mosaddad, S. A. (2020)	“Current biocompatible materials in oral regeneration: A comprehensive overview of composite materials.”	The medicine used in the study is not a traditional pharmaceutical medicine, but rather biocompatible materials used in oral regeneration, specifically composite materials. The study provides a comprehensive overview of various composite materials used in dental applications, including their properties, fabrication methods, and applications in dental treatments.	Review article.	The results of the study indicate that composite materials have several advantages over traditional materials used in dental applications, such as improved mechanical properties, biocompatibility, and aesthetics. The authors also discuss the limitations and future directions of research in the field of composite materials in dental applications. Overall, the study provides valuable insights into the current trends and developments in biocompatible composite materials in oral
15	2022	Omi, M., & Mishina, Y. (2022)	“Roles of osteoclasts in alveolar bone remodeling. genesis.”	The medicine used in the study is not a traditional pharmaceutical medicine, but rather the biological cells called osteoclasts, which are involved in alveolar bone remodeling.	Review article.	The results of the study show that osteoclasts play important roles in alveolar bone remodeling, including bone resorption and remodeling, tooth eruption, and maintenance of periodontal health.
16	2021	Mohammadi, B., Abdoli, Z., & Anbarzadeh, E. (2021)	“Investigation of the Effect of Abutment Angle Tolerance on the Stress Created in the Fixture and Screw in Dental Implants Using Finite Element Analysis.”	The medicine used in this research is not a traditional pharmaceutical medicine, but rather the dental implants and abutments used in the study. The study uses finite element analysis to investigate the effect of abutment angle tolerance on the stress created in the fixture and screw of dental implants.	Finite element analysis.	The results of the study suggest that the abutment angle tolerance has a significant effect on the stress created in the fixture and screw of dental implants. The authors recommend that clinicians should consider the abutment angle tolerance during implant placement to minimize the risk of implant failure due to excessive stress. The study highlights the importance of using finite element analysis in dental implant research to evaluate the mechanical behavior of implants under various loading conditions.
17	2022	Cinar, I. C., Gultekin, B. A., Saglanmak, A., Akay, A. S., Zboun, M., & Mijiritsky, E. (2022)	“Comparison of Allogeneic Bone Plate and Guided Bone Regeneration Efficiency in Horizontally Deficient Maxillary Alveolar Ridges.”	The study does not involve any medicine, as it compares two different techniques (allogeneic bone plate and guided bone regeneration) for maxillary alveolar ridge reconstruction.	Comparative Study.	The study found that both allogeneic bone plate and guided bone regeneration techniques were effective in horizontally deficient maxillary alveolar ridge reconstruction, but the allogeneic bone plate technique provided better outcomes in terms of bone height gain and reduction in the width of the ridge. However, both techniques showed similar success rates for implant placement.
18	2023	Zhang Longo, et al. (2020)	“Soft‐tissue dimensional change following guided bone regeneration on peri‐implant defects using soft‐type block or particulate bone substitutes: 1‐year outcomes of a randomized controlled clinical trial.”	It focuses on the use of two different types of bone substitutes (soft-type block or particulate bone substitutes) in guided bone regeneration for peri-implant defects and their effect on soft-tissue dimensional change around implants.	Randomized Trial	The study found that both soft-type block and particulate bone substitutes are effective in guided bone regeneration for peri-implant defects, and both result in similar soft-tissue dimensional changes around the implants after one year.
19	2022	Cinar, I. C., Gultekin, B. A., Saglanmak, A., Akay, A. S., Zboun, M., & Mijiritsky, E. (2022)	“Comparison of Allogeneic Bone Plate and Guided Bone Regeneration Efficiency in Horizontally Deficient Maxillary Alveolar Ridges.”	The study compares two surgical techniques used for bone augmentation.	Clinical comparison.	The results of the study suggest that both techniques are effective, but allogeneic bone plates may have advantages over guided bone regeneration in certain situations.
20	2023	Abraham, A. M., & Venkatesan, S. (2023)	“A review on application of biomaterials for medical and dental implants.”	The study does not focus on a specific medicine used for medical or dental implants. Instead, it is a general review of the application of biomaterials for such implants. Biomaterials can include a wide range of materials such as metals, ceramics, polymers, and composites.	Literature review.	The study is a review article that explores the use of biomaterials for medical and dental implants. It was published in 2023 in the Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications.