Table 1: Differentiation of ATN and AIN: Possible small differences [7,11,14,17,23-25].
|
ATN |
AIN |
After ingestion of NSAIDs |
yes |
yes |
Dehydration |
yes |
no |
Allergic manifestation |
no |
yes |
Nonspecific symptoms |
no |
yes |
After ingestion of NSAIDs and Alcohol consumption |
possible |
no |
Eosinophilia |
no |
yes |
Urine sediment |
No or only minimal changes, hyaline casts, RTECs, RTEC casts, course granular casts, “muddy brown” casts |
WBCs, WBC casts, RBCs, occasional RBC casts, RTECs, RTEC casts
|
Urine dipstick |
−/+ protein |
−/+ protein, +/++ LE, +/++ blood |
AKI |
oligo/anuric |
mild, non-oliguric |
Kidney tenderness |
yes |
rare |
Treatment |
stop the medication |
stop the medication corticosteroids |