Table 1: Differentiation of ATN and AIN: Possible small differences [7,11,14,17,23-25].

 

ATN

AIN

After ingestion of NSAIDs

yes

yes

Dehydration

yes

no

Allergic manifestation

no

yes

Nonspecific symptoms

no

yes

After ingestion of NSAIDs and Alcohol consumption

possible

no

Eosinophilia

no

yes

Urine sediment

No or only minimal changes, hyaline casts, RTECs, RTEC casts, course granular casts, “muddy brown” casts

WBCs, WBC casts, RBCs, occasional RBC casts, RTECs, RTEC casts

 

Urine dipstick

−/+ protein

−/+ protein, +/++ LE, +/++ blood

AKI

oligo/anuric

mild, non-oliguric

Kidney tenderness

yes

rare

Treatment

stop the medication

stop the medication

corticosteroids