Table 3: Report of Major Adverse Reactions of Listed Nano-particles.

Name of drug

Active ingredient

Dosage form route of administration

Main adverse reactions reported

Doxil®

Adriamycin

Injection; Intravenous injection

Leukopenia (which occurs in nearly half of patients); Nausea, weakness, hair loss, fever, diarrhea, etc (≥ 5%)

Rapamune®

Sirolimus

Tablet; Oral

Thrombocytopenia, anemia, fever, hypertension, etc. (about 10%)

Emend®

Aprepitant

Capsule; Oral

Constipation (7-8%), anorexia (about 3%)

Abraxane®

Paclitaxel

Injection; intravenous drip

Hair loss, neutropenia, ECG abnormalities, muscle joint pain, elevated AST levels, etc. (≥ 20%)

KaiLai®

Doxorubicin

Injection; intravenous drip

Bone marrow suppression