Nanoparticles

Structure

Measure

Advantages in reversing resistance of anticancer drugs

Liposome

Bilayer structure

25-1000 nm

Low toxicity; Low immunogenicity; Targeting

Polymer nanoparticles

Core-shell structure

10-1000 nm

Can improve that efficacy of drug molecule; Can enhance drug stability

Polymer micelle

Single molecular layer structure

10-100 nm

Targeting; Can improve the stability of insoluble drugs

Drug-polymer conjugate

skeleton structure

50-1000 nm

High drug loading

Dendritic polymer

Lineardendritic structure

10-130 nm

High stability

Nano shell

Hollow shell structure

10-500 nm

Sustainable drug release; Flexible adjustability

Magnetic nanoparticles

Core-shell structure

10-1000 nm

Has special magnetic guiding property

drug nanocrystal

Crystalline structure

10-1000 nm

Is not restrict by encapsulation efficiency, and has large effective drug amount; Can improve that solubility of insoluble drug;

Extracellular vesicle

Bilayer structure

30-200 nm

Natural source, low immunogenicity; Is easy to be taken up by target cell; Strong targeting