Table 1: Hydrodynamic diameter (A) or zeta potential (B) of the nanoparticles without the protein corona or with the protein coronas by incubating with BSA for 1 h. Significant difference vs in water group (*p < 0.01).
(A)
MNPs | c(RGDyK)-MNPs | |||
DLS (nm) | Water | BSA | Water | BSA |
0 h | 112.4 ± 4.9 | 112.4 ± 4.9 | 118.5 ± 7.6 | 118.5 ± 7.6 |
1 h | 121.0 ± 4.7 | 156.6 ± 3.8* | 112.7 ± 3.9 | 239.4 ± 1.9* |
(B)
Zeta potential (mV) | MNPs | c(RGDyK)-MNPs | ||
Water | BSA | Water | BSA | |
0 h | -20.4 ± 1.3 | -20.4 ± 1.3 | -30.4 ± 1.3 | -30.4 ± 1.3 |
1 h | -20.7 ± 1.0 | -14.3 ± 0.9* | -30.7 ± 1.0 | -15.7 ± 1.4* |