Table 1: Hydrodynamic diameter (A) or zeta potential (B) of the nanoparticles without the protein corona or with the protein coronas by incubating with BSA for 1 h. Significant difference vs in water group (*p < 0.01).

(A)

MNPs c(RGDyK)-MNPs
DLS (nm) Water BSA Water BSA
0 h 112.4 ± 4.9 112.4 ± 4.9 118.5 ± 7.6 118.5 ± 7.6
1 h 121.0 ± 4.7 156.6 ± 3.8* 112.7 ± 3.9 239.4 ± 1.9*

(B)

Zeta potential (mV) MNPs c(RGDyK)-MNPs
Water BSA Water BSA
0 h -20.4 ± 1.3 -20.4 ± 1.3 -30.4 ± 1.3 -30.4 ± 1.3
1 h -20.7 ± 1.0 -14.3 ± 0.9* -30.7 ± 1.0 -15.7 ± 1.4*