Table 5: Cross-sectional models for the associations between maternal characteristics and continuous scores on the HADS-depression (HADS-D) and HADS-anxiety (HADS-A) subscales in late pregnancy.

 

Maternal characteristics

HADS-D

HADS-A

Crude β

Adjusted β

Crude β

Adjusted β

Demographics

Maternal age (years)

≤ 30

Ref

-

Ref

-

30-34

0.15 (-0.09-0.39)

0.07 (-0.13-0.27)

≥ 35

0.48 (0.10-0.86)

0.14 (-0.17-0.46)

Level of education

High

Ref

Ref

Ref

Ref

Intermediate

0.86 (0.59-1.13)

0.77 (0.43-1.11)

0.27 (0.05-0.50)

0.31 (0.03-0.59)

Low

1.23 (0.41-2.05)

0.78 (-0.18-1.73)

1.19 (0.50-1.88)

1.37 (0.54-2.20)

Net household income < €2500/mo/mo(€/month)

0.82 (0.50-1.14)

-

0.58 (0.31-0.85)

-

Non-Dutch

0.34 (-0.28-0.97)

-

0.12 (-0.38-0.63)

-

Not living together with partner

0.55 (-0.09-1.20)

-

0.89 (0.36-1.43)

-

Medical history

Multiparity

0.94 (0.72-1.17)

0.98 (0.69-1.26)

0.15 (-0.04-0.34)

0.22 (-0.02-0.46)

Pre-pregnancy BMI

Normal weight

Ref

Ref

Ref

-

Underweight

0.35 (-0.30-1.00)

0.28 (-0.50-1.06)

0.24 (-0.30-0.78)

Overweight/obese

0.56 (0.28-0.83)

0.37 (0.03-0.71)

0.12 (-0.11-0.34)

Time to pregnancy

< 1 month

Ref

-

Ref

-

1-12 months

-0.20 (-0.47-0.06)

0.01 (-0.22-0.22)

> 12 months

-0.17 (-0.56-0.22)

0.08 (-0.24-0.41)

Previous miscarriages

0.38 (0.10-0.65)

-

0.04 (-0.18-0.27)

-

Use of reproductive techniques

-0.16 (-0.43-0.42)

-

0.10 (-0.27-0.46)

-

Chronic diseases

0.17 (-0.13-0.46)

-

0.07 (-0.18-0.31)

-

Pregnancy-related characteristics

Unplanned pregnancy

1.09 (0.66-1.51)

-

0.30 (-0.05-0.66)

-

Infection during pregnancy

0.41 (0.18-0.64)

-

0.33 (0.14-0.52)

0.22 (-0.02-0.46)

Severe nausea

0.98 (0.50-1.45)

-

0.68 (0.28-1.08)

-

Extreme fatigue

2.04 (1.64-2.44)

1.58 (1.10-2.07)

1.03 (0.69-1.37)

0.65 (0.22-1.07)

Negative prenatal diagnostics

-0.06 (-0.43-0.31)

-

-0.06 (-0.37-0.25)

-

Health behaviour during pregnancy

Smoking

1.43 (0.72-2.14)

-

0.53 (-0.06-1.13)

-

Alcohol

0.10 (-0.60-0.79)

-

0.62 (0.04-1.19)

-

High caffeine consumption

-0.25 (-0.51-0.01)

-

0.09 (-0.13-0.30)

-

Physical exercise

≥ 150 min/week

Ref

Ref

Ref

Ref

< 150 m/week

0.32 (0.09-0.56)

0.21 (-0.09-0.51)

0.13 (-0.07-0.33)

0.27 (0.02-0.52)

No

1.50 (1.09-1.91)

1.60 (1.08-2.11)

0.44 (0.11-0.78)

0.49 (0.06-0.92)

Psychosocial characteristics

Negative life event score

0

Ref

Ref

Ref

Ref

≤ 50

0.33 (-0.27-0.93)

0.76 (0.13-1.40)

1.16 (0.68-1.64)

1.38 (0.86-1.91)

> 50

0.76 (0.06-1.47)

0.72 (-0.07-1.51)

1.94 (1.37-2.51)

1.78 (1.11-2.45)

Use of medication for depression or anxiety disorders

1.01 (-0.55-2.57)

-

1.98 (0.65-3.31)

-

History of depression

0.87 (0.60-1.13)

0.60 (0.26-0.93)

1.16 (0.94-1.38)

1.08 (0.80-1.37)

Family history of depression

0.44 (0.18-0.70)

-

0.39 (0.17-0.60)

-

 

-Variable eliminated from the multivariable model.