Active Surveillance (n = 118)

Primary Focal Cryotherapy (n = 61)

P-value

Mean Bowel Function

94.54

94.00

0.947

Mean Urinary Function

83.76

86.60

0.278

Mean Sexual Function

54.14

38.75

< 0.001

Mean Rate of Ejaculation^*

4.17

3.68

0.061

Mean Rate of Sensation of Orgasm^#

4.02

4.00

0.351

Mean Satisfaction with Overall Sex Life

2.91

2.48

0.086

Use of Alpha Blockers

17 (14.4%)

26 (42.6%)

< 0.001

Use of 5-α-Reductase Inhibitors

7 (5.9%)

23 (37.7%)

< 0.001

Use of PDE-5 Inhibitors

27 (24.3%)

16 (30.2%)

0.425

Median Time to Survey Completion

38 months

43 months

0.586

Anxiety About Post-Treatment PSA

0.75

0.68

0.494

Fear of PCa Recurrence

8.57

8.54

0.551