Table 4: Univariate analysis of factors associated with better outcome in terms of progression free survival and overall survival.

n = 30

Univariate Analysis

Median OS, 95% CI

p-valor

Univariate Analysis

Median PFS, 95% CI

p-value

Sex

Male

Female

 

19.3 (20.2-35.9)

36.7 (18.4-40.0)

 

 

0.552

 

10.4  (8.58-14.5)

15.8 (13.5-18.6)

 

 

0.083

Performance Status

0-1

2

 

36.7 (20.8-42.3)

18.4 (18.4-36.2)

 

 

0.488

 

11 (5.57-16.4)

11.1 (8.2-13.9)

 

 

0.903

Histology

Non-Squamous

Squamous

 

36.7 (24.7-40.9)

13.9  (9.58-20.6)

 

 

0.005*

 

12.1 (10.5-13.6)

8.1  (4.9-11.2)

 

 

0.041*

Mediastinal Lymphnode infiltration

Yes (N2-3)

No (N0-1)

 

17.7 (16.2-31.8)

42.7  (28.4-45.3)

 

 

0.05*

 

10.4 (5.9-14.8)

14.7 (11.2-18.1)

 

 

0.072

Brain Metastases

Yes

No

 

19.3 (17.3-31.3)

26.7 (20.4-39.7)

 

 

0.677

 

12.1 (10.7-13.4)

10.4 (7.7-13.0)

 

0.956

 

Maintenance Treatment

Yes

No

 

42.7 (25.6-48.3)

17.7 (15.4-28.2)

 

 

0.068

 

12.1 (8.2-15.9)

9.6 (6.4-12.8)

 

 

0.041*