Table 2: Main biochemical data of patients affected by COVID-19 pneumonia divided by type of received treatment.

N/L

5.6 (3.5-9.6)

6.3 (3.5-10.4)

7.8 (2.6-24.7)

4.9 (3.3-9.0)

6.4 (3.9-11.6)

0.11

Platelets (1000/µl)

206 (152-275)

192 (148-259)

222 (143-248)

211 (161-292)

210 (141-269)

0.19

aPTT (sec)

1.0 (0.9-1.1)

1.0 (0.9-1.1)

1.0 (0.9-1.0)

1.0 (0.9-1.1)

1.0 (0.9-1.1)

0.71

INR

1.4 (1.2-2.6)

1.5 (1.3-2.8)

/

1.3 (1.2-2.5)

1.3 (1.2-4.6)

0.79

D-dimer (ng/ml)

1081 (620-2102)

1245 (736-2411)

1142 (658-3089)

986 (536-2098)

1174 (749-2026)

0.25

HS troponin I (µg/l)

12.8 (4.8-37.7)

24.7 (5.1-56.0)°

4.0 (3.0-8.7)

8.0 (3.2-23.4)§°

23.7 (12.1-47.9)§

< 0.001

BNP (pg/ml)

76 (31-180)

67 (13-195)

53 (31-68)

74 (30-157)

132 (44-227)

0.46

PCT (ng/ml)

0.14 (0.07-0.45)

0.18 (0.06-0.81)

0.31 (0.07-1.82)

0.12 (0.06-0.29)§

0.18 (0.09-0.52)§

0.008

CRP (mg/l)

80.9 (31.5-144.2)

91.7 (35.4-145.8)

102.7 (36.7-191.8)

72.9 (24.5-130.4)§

91.7 (51.2-157.1)§

0.05

Ferritin (ng/ml)

811 (368-1903)

1704 (629-3584)°

/

743 (273-1450)°

793 (538-2624)

0.04

Cholinesterase (U/L)

7741

(6132-9367)

8083

(6718-9378)*

6851

(5868-7731)

7945

(6211-9468)§

6402

(5534-8552)

0.01

Serum creatinine (mg/dl)

0.9 (0.8-1.3)

1.0 (0.7-1.3)

1.1 (0.9-1.8)

0.9 (0.8-1.2)

1.0 (0.7-1.4)

0.37

Proteinuria (mg/l)

300 (150-1000)

300 (37-1000)

650 (300-2500)

300 (150-500)§

300 (150-1000)§

0.02

Total bilirubin (mg/dl)

0.6 (0.4-0.8)

0.6 (0.4-0.8)

0.7 (0.4-1.0)

0.6 (0.4-0.8)

0.6 (0.4-0.8)

0.92

ALT (U/L)

29 (19-48)

32 (22-54)°

24 (15-33)

26 (17-47)°

29 (18-45)

0.04

AST (U/L)

36 (27-57)

40 (29-62)

45 (41-53)

34 (25-51)

40 (30-57)

0.02

Gamma-GT (U/L)

51 (27-93)

60 (29-120)

40 (22-58)

43 (25-85)

54 (36-84)

0.05

LDH (U/L)

320 (242-417)

333 (245-487)

385 (267-503)

298 (228-397)§

348 (269-466)§

0.01

Data are expressed as median ۧ interquartile range (IQR) when not specified.

*Significant difference between G1 and G4; §Significant difference between G3 and G4; °Significant difference between G1 and G3.

Abbreviations: N/L: Neutrophils/leucocytes ratio; aPTT: Activated partial thromboplastin time; INR: International normalized ratio; PCT: Procalcitonin; CRP: C-reactive protein; BNP: B-type natriuretic peptide; ALT: Alanine transferase; AST: Aspartate aminotransferase; LDH: Lactate dehydrogenase; gamma-GT: Gamma-glutamyltransferase.